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Table 2 Composition of polyunsaturated FAs in major tissues

From: The effect of western diet on mice brain lipid composition

 

Chow [μg/kg]

Serum [μg/L]

Brain [%]

Liver [%]

Retroperitoneal adipose tissue [%]

Epididymal adipose tissue [%]

Subcutaneous adipose tissue [%]

 

10%

60%

SD

HFD

SD

HFD

SD

HFD

SD

HFD

SD

HFD

SD

HFD

SFA

205.08

671.00

971.92 ± 253.18

1766.61 ± 353.61#

46.13 ± 1.06

46.82 ± 2.14

37.41 ± 0.86

38.03 ± 4.72

33.75 ± 2.46

29.73 ± 1.64*

29.08 ± 1.53

29.28 ± 1.63

31.99 ± 1.39

28.80 ± 2.29*

MUFA

131.09

455.75

1079.97 ± 340.71

1227.99 ± 244.16

32.35 ± 2.64

30.99 ± 2.75

41.26 ± 2.56

39.15 ± 11.23

62.51 ± 2.16

62.06 ± 1.73

66.86 ± 1.29

62.58 ± 1.43*

64.19 ± 1.44

63.03 ± 2.17

16:2 n-6

–

–

0.10 ± 0.02

0.40 ± 0.15

0.01 ± 0.00

0.01 ± 0.01

0.003 ± 0.000

0.020 ± 0.010*

0.01 ± 0.00

0.01 ± 0.01

0.01 ± 0.00

0.01 ± 0.00*

0.003 ± 0.000

0.02 ± 0.01#

LA

25.83

95.00

329.16 ± 24.65

870.96 ± 105.11#

0.38 ± 0.08

0.72 ± 0.08#

6.40 ± 0.46

11.56 ± 2.34*

3.02 ± 0.28

7.46 ± 0.10#

3.42 ± 0.51

7.51 ± 0.31#

3.16 ± 0.17

7.51 ± 0.15#

20:2 n-6

0.89

0.40

3.39 ± 0.48

8.88 ± 2.05#

0.08 ± 0.02

0.15 ± 0.03*

0.09 ± 0.01

0.17 ± 0.05*

0.07 ± 0.01

0.14 ± 0.03#

0.05 ± 0.01

0.11 ± 0.02#

0.05 ± 0.01

0.11 ± 0.02#

DGLA

0.26

1.25

29.86 ± 5.51

34.00 ± 13.69

0.35 ± 0.04

0.38 ± 0.01

1.35 ± 0.11

0.65 ± 0.17#

0.08 ± 0.02

0.06 ± 0.00*

0.05 ± 0.01

0.03 ± 0.02*

0.07 ± 0.01

0.04 ± 0.01*

ARA

0.48

1.75

140.57 ± 30.17

313.94 ± 49.40#

7.93 ± 0.61

8.11 ± 0.64

8.19 ± 0.87

6.28 ± 2.83

0.10 ± 0.03

0.10 ± 0.02

0.06 ± 0.02

0.04 ± 0.03

0.11 ± 0.02

0.07 ± 0.02*

AdA

0.11

0.75

1.37 ± 0.20

2.81 ± 0.534*

2.06 ± 0.25

2.01 ± 0.25

0.14 ± 0.02

0.17 ± 0.05

0.02 ± 0.01

0.01 ± 0.00*

0.01 ± 0.01

0.01 ± 0.00

0.01 ± 0.01

0.01 ± 0.00

PUFA n-6

27.76

103.13

509.63 ± 50.28

1232.70 ± 99.52#

11.22 ± 0.96

11.52 ± 0.64

16.62 ± 1.38

18.93 ± 5.24

3.30 ± 0.32

7.79 ± 0.09#

3.61 ± 0.53

7.72 ± 0.23#

3.42 ± 0.18

7.77 ± 0.19#

ALA

0.07

0.25

5.24 ± 1.80

9.52 ± 2.24*

0.02 ± 0.01

0.02 ± 0.01

0.10 ± 0.03

0.18 ± 0.06*

0.01 ± 0.01

0.01 ± 0.01

0.01 ± 0.00

0.01 ± 0.01

0.01 ± 0.01

0.01 ± 0.00

ETA

–

–

2.53 ± 0.43

2.37 ± 0.65

–

–

0.06 ± 0.01

0.03 ± 0.01*

0.01 ± 0.00

0.01 ± 0.00

0.01 ± 0.00

0.01 ± 0.01

0.01 ± 0.00

0.01 ± 0.00

EPA

0.19

0.50

39.66 ± 9.47

18.94 ± 2.29#

0.33 ± 0.03

0.15 ± 0.02 #

1.71 ± 0.12

0.31 ± 0.11#

0.12 ± 0.02

0.03 ± 0.00#

0.13 ± 0.02

0.05 ± 0.04#

0.12 ± 0.02

0.02 ± 0.01#

DPA

0.19

0.63

2.61 ± 0.39

7.59 ± 1.90#

0.36 ± 0.05

0.31 ± 0.06

0.23 ± 0.04

0.32 ± 0.09

0.03 ± 0.01

0.02 ± 0.01

0.02 ± 0.01

0.01 ± 0.00

0.03 ± 0.01

0.01 ± 0.00#

DHA

0.04

0.25

28.40 ± 6.74

68.66 ± 7.68#

8.91 ± 0.57

9.71 ± 0.78

2.36 ± 0.29

2.85 ± 1.28

0.03 ± 0.01

0.01 ± 0.01*

0.02 ± 0.00

0.01 ± 0.01

0.02 ± 0.00

0.01 ± 0.00

PUFA n-3

0.48

1.63

78.43 ± 17.61

108.08 ± 8.18*

9.62 ± 0.60

10.19 ± 0.79

4.46 ± 0.37

3.69 ± 1.50

0.20 ± 0.04

0.08 ± 0.01#

0.19 ± 0.01

0.10 ± 0.06*

0.18 ± 0.02

0.06 ± 0.02#

  1. p-value from t-test: * < 0.05, # < 0.001, AdA – adrenic acid (22:4 n-6), ALA – α-linolenic acid (18:3 n-3), ARA – arachidonic acid (20:4 n-6), DGLA –dihomo-γ-linolenic acid (20:3 n-6), DHA – docosahexaenoic acid (22:6 n-3), DPA – docosapentaenoic acid (22:5 n-3), EPA – eicosapentaenoic acid (20:5 n-3), ETA – eicosatetraenoic acid (20:4 n-3), LA – linoleic acid (18:2 n-6), MUFA – monounsaturated fatty acids, PUFA – polyunsaturated fatty acids, SFA – saturated fatty acid
  2. Boldface, major groups of fatty acid
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Nutrition & Metabolism

ISSN: 1743-7075

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