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Table 2 Composition of polyunsaturated FAs in major tissues

From: The effect of western diet on mice brain lipid composition

 Chow [μg/kg]Serum [μg/L]Brain [%]Liver [%]Retroperitoneal adipose tissue [%]Epididymal adipose tissue [%]Subcutaneous adipose tissue [%]
 10%60%SDHFDSDHFDSDHFDSDHFDSDHFDSDHFD
SFA205.08671.00971.92 ± 253.181766.61 ± 353.61#46.13 ± 1.0646.82 ± 2.1437.41 ± 0.8638.03 ± 4.7233.75 ± 2.4629.73 ± 1.64*29.08 ± 1.5329.28 ± 1.6331.99 ± 1.3928.80 ± 2.29*
MUFA131.09455.751079.97 ± 340.711227.99 ± 244.1632.35 ± 2.6430.99 ± 2.7541.26 ± 2.5639.15 ± 11.2362.51 ± 2.1662.06 ± 1.7366.86 ± 1.2962.58 ± 1.43*64.19 ± 1.4463.03 ± 2.17
16:2 n-60.10 ± 0.020.40 ± 0.150.01 ± 0.000.01 ± 0.010.003 ± 0.0000.020 ± 0.010*0.01 ± 0.000.01 ± 0.010.01 ± 0.000.01 ± 0.00*0.003 ± 0.0000.02 ± 0.01#
LA25.8395.00329.16 ± 24.65870.96 ± 105.11#0.38 ± 0.080.72 ± 0.08#6.40 ± 0.4611.56 ± 2.34*3.02 ± 0.287.46 ± 0.10#3.42 ± 0.517.51 ± 0.31#3.16 ± 0.177.51 ± 0.15#
20:2 n-60.890.403.39 ± 0.488.88 ± 2.05#0.08 ± 0.020.15 ± 0.03*0.09 ± 0.010.17 ± 0.05*0.07 ± 0.010.14 ± 0.03#0.05 ± 0.010.11 ± 0.02#0.05 ± 0.010.11 ± 0.02#
DGLA0.261.2529.86 ± 5.5134.00 ± 13.690.35 ± 0.040.38 ± 0.011.35 ± 0.110.65 ± 0.17#0.08 ± 0.020.06 ± 0.00*0.05 ± 0.010.03 ± 0.02*0.07 ± 0.010.04 ± 0.01*
ARA0.481.75140.57 ± 30.17313.94 ± 49.40#7.93 ± 0.618.11 ± 0.648.19 ± 0.876.28 ± 2.830.10 ± 0.030.10 ± 0.020.06 ± 0.020.04 ± 0.030.11 ± 0.020.07 ± 0.02*
AdA0.110.751.37 ± 0.202.81 ± 0.534*2.06 ± 0.252.01 ± 0.250.14 ± 0.020.17 ± 0.050.02 ± 0.010.01 ± 0.00*0.01 ± 0.010.01 ± 0.000.01 ± 0.010.01 ± 0.00
PUFA n-627.76103.13509.63 ± 50.281232.70 ± 99.52#11.22 ± 0.9611.52 ± 0.6416.62 ± 1.3818.93 ± 5.243.30 ± 0.327.79 ± 0.09#3.61 ± 0.537.72 ± 0.23#3.42 ± 0.187.77 ± 0.19#
ALA0.070.255.24 ± 1.809.52 ± 2.24*0.02 ± 0.010.02 ± 0.010.10 ± 0.030.18 ± 0.06*0.01 ± 0.010.01 ± 0.010.01 ± 0.000.01 ± 0.010.01 ± 0.010.01 ± 0.00
ETA2.53 ± 0.432.37 ± 0.650.06 ± 0.010.03 ± 0.01*0.01 ± 0.000.01 ± 0.000.01 ± 0.000.01 ± 0.010.01 ± 0.000.01 ± 0.00
EPA0.190.5039.66 ± 9.4718.94 ± 2.29#0.33 ± 0.030.15 ± 0.02 #1.71 ± 0.120.31 ± 0.11#0.12 ± 0.020.03 ± 0.00#0.13 ± 0.020.05 ± 0.04#0.12 ± 0.020.02 ± 0.01#
DPA0.190.632.61 ± 0.397.59 ± 1.90#0.36 ± 0.050.31 ± 0.060.23 ± 0.040.32 ± 0.090.03 ± 0.010.02 ± 0.010.02 ± 0.010.01 ± 0.000.03 ± 0.010.01 ± 0.00#
DHA0.040.2528.40 ± 6.7468.66 ± 7.68#8.91 ± 0.579.71 ± 0.782.36 ± 0.292.85 ± 1.280.03 ± 0.010.01 ± 0.01*0.02 ± 0.000.01 ± 0.010.02 ± 0.000.01 ± 0.00
PUFA n-30.481.6378.43 ± 17.61108.08 ± 8.18*9.62 ± 0.6010.19 ± 0.794.46 ± 0.373.69 ± 1.500.20 ± 0.040.08 ± 0.01#0.19 ± 0.010.10 ± 0.06*0.18 ± 0.020.06 ± 0.02#
  1. p-value from t-test: * < 0.05, # < 0.001, AdA – adrenic acid (22:4 n-6), ALA – α-linolenic acid (18:3 n-3), ARA – arachidonic acid (20:4 n-6), DGLA –dihomo-γ-linolenic acid (20:3 n-6), DHA – docosahexaenoic acid (22:6 n-3), DPA – docosapentaenoic acid (22:5 n-3), EPA – eicosapentaenoic acid (20:5 n-3), ETA – eicosatetraenoic acid (20:4 n-3), LA – linoleic acid (18:2 n-6), MUFA – monounsaturated fatty acids, PUFA – polyunsaturated fatty acids, SFA – saturated fatty acid
  2. Boldface, major groups of fatty acid