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Fig. 1 | Nutrition & Metabolism

Fig. 1

From: Curcumin prevents high-fat diet-induced hepatic steatosis in ApoE−/− mice by improving intestinal barrier function and reducing endotoxin and liver TLR4/NF-κB inflammation

Fig. 1

Effects of curcumin on liver histology and hepatic TG content in HFD-fed ApoE−/− mice. ApoE−/− mice were fed a normal diet, high-fat diet and high-fat diet supplemented with 0.1% curcumin (w/w) for 16 weeks, histological analysis of steatosis in liver sections stained with H&E (a) or Oil Red O (b) (magnification 200 ×). Hepatic TG content (c). Histological changes of steatosis in the liver were semi-quantitative and expressed as steatosis scores (d). Results are mean ± SEM (n = 10 per group). ##P < 0.01 versus control group; *P < 0.05, **P < 0.01 versus HF group. Control, normal diet; HF, high-fat diet; HF + Curcumin, high-fat diet supplemented with curcumin

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