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Fig. 4 | Nutrition & Metabolism

Fig. 4

From: Curcumin prevents high-fat diet-induced hepatic steatosis in ApoE−/− mice by improving intestinal barrier function and reducing endotoxin and liver TLR4/NF-κB inflammation

Fig. 4

Effects of curcumin on hepatic TLR4 and MyD88 expression in HFD-fed ApoE−/− mice. ApoE−/− mice were fed a normal diet, high-fat diet and high-fat diet supplemented with 0.1% curcumin (w/w) for 16 weeks. (a) TLR4 expression in the liver was measured by immunohistochemical staining. Representative images of the control, HF and HF + curcumin groups (200 × magnification). (b) The protein expression levels of hepatic TLR4 and MyD88 were analyzed by Western blotting. (Top panel) Representative blot, (Bottom panel) Quantitative analysis of panel B. Results are mean ± SEM (n = 10 per group). #P < 0.05 versus control group, *P < 0.05 versus HF group. Control, normal diet; HF, high-fat diet; HF + Curcumin, high-fat diet supplemented with curcumin

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Nutrition & Metabolism

ISSN: 1743-7075

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