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Table 3 Biochemical parameters for mice evaluated in this study

From: Curcumin prevents high-fat diet-induced hepatic steatosis in ApoE−/− mice by improving intestinal barrier function and reducing endotoxin and liver TLR4/NF-κB inflammation

 

Control

HF

HF + Curcumin

Body weight gain (g)

8.6 ± 2.5

15.1 ± 4.2 a

9.8 ± 3.4b

Liver weight (g)

1.34 ± 0.09

1.96 ± 0.12 a

1.53 ± 0.05b

Total food intake (g)

635.6 ± 22.3

637.9 ± 21.5

632.5 ± 20.8

ALT (U/L)

25.2 ± 3.8

30.5 ± 2.7 a

28.7 ± 6.0

AST (U/L)

30.7 ± 5.4

65.4 ± 15 a

42.8 ± 3.5 b

TC (mmol/L)

22.54 ± 4.27

36.03 ± 3.43 a

24.60 ± 6.64b

TG (mmol/L)

1.50 ± 0.80

1.96 ± 1.01 a

1.69 ± 0.50

LDL-C (mmol/L)

18.76 ± 4.62

31.56 ± 4.81 a

19.98 ± 5.24 b

HDL-C (mmol/L)

7.29 ± 1.51

6.78 ± 1.46

9.07 ± 1.96 b

  1. Values are mean ± SEM (n = 10 per group). Control, normal diet; HF, high-fat diet; HF + Curcumin, high-fat diet supplemented with curcumin
  2. a Significant difference between the Control and HF groups(p < 0.05)
  3. bSignificant difference between the HF and HF + Curcumin groups (p < 0.05)