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Table 2 Adjusted weight change for iso-energetic replacement of macronutrients

From: The association of dietary macronutrients with anthropometric changes, using iso-energetic substitution models: Tehran lipid and glucose study

Type of macronutrient Substitution

All

Men

Women

β

P-value

β

P-value

β

P-value

Carbohydrate ↑

 Fat ↓

0.00

0.96

−0.03

0.04

0.01

0.65

 Protein ↓

−0.01

0.57

−0.04

0.25

0.01

0.71

Carbohydrate ↑

 SFA ↓

−0.01

0.47

−0.06

0.02

0.01

0.65

 MUFA ↓

−0.03

0.11

−0.06

0.02

−0.00

0.90

 PUFA ↓

−0.02

0.24

−0.05

0.03

0.01

0.62

 Protein ↓

−0.03

0.10

− 0.03

0.14

− 0.00

0.92

Carbohydrate ↑

 Fat ↓

− 0.01

0.68

− 0.02

0.33

0.01

0.52

 Plant Protein ↓

−0.02

0.47

−0.03

0.22

0.01

0.72

 Animal Protein ↓

−0.02

0.46

−0.04

0.25

0.01

0.73

Carbohydrate ↑

 SFA ↓

−0.01

0.56

−0.02

0.47

0.01

0.68

 MUFA ↓

−0.03

0.14

−0.05

0.07

−0.00

0.95

 PUFA ↓

−0.02

0.33

−0.04

0.11

0.01

0.51

 Plant Protein ↓

−0.03

0.10

−0.06

0. 17

−0.00

0.92

 Animal Protein ↓

−0.03

0.01

−0.04

0. 86

−0.00

0.92

Plant protein ↑

 Animal protein ↓

0.01

0.46

−0.04

0.04

0.01

0.46

 Carbohydrate ↓

−0.08

0.37

−0.04

0.03

−0.01

0.69

 Fat ↓

−0.07

0.43

−0.04

0.04

−0.09

0.62

Plant protein ↑

 Animal protein ↓

−0.69

0.05

−0.08

0.01

0.03

0.96

 Starch ↓

−0.17

0.12

−0.05

0.03

−0.18

0.39

 Non-starch ↓

−0.72

0.04

−0.08

0.00

−0.00

0.10

 Fat ↓

−0.71

0.04

−0.08

0.01

0.03

0.96

Plant protein ↑

 Animal protein ↓

0.01

0.52

−0.05

0.02

0.01

0.57

 Carbohydrate ↓

−0.11

0.23

−0.06

0.00

−0.05

0.77

 SFA ↓

−0.06

0.52

−0.04

0.04

−0.03

0.86

 MUFA ↓

−0.08

0.37

−0.05

0.02

−0.06

0.74

 PUFA ↓

−0.09

0.30

−0.05

0.01

−0.11

0.54

Plant protein ↑

 Animal protein ↓

−0.84

0.02

−0.11

0.00

0.14

0.84

 Starch ↓

−0.20

0.07

−0.06

0.00

−0.15

0.49

 Non-starch ↓

−0.86

0.02

−0.11

0.00

0.11

0.87

 SFA ↓

−0.76

0.03

−0.10

0.00

0.17

0.79

 MUFA ↓

−0.76

0.03

−0.093

0.01

0.06

0.93

 PUFA ↓

−0.86

0.02

−0.11

0.00

−0.00

0.99

  1. SFA Saturated fatty acid, MUFA Mono-unsaturated fatty acids, PUFA Poly-unsaturated fatty acids. Non-starch carbohydrates: simple sugars. The percentage of energy from macronutrients divides by 5 to calculate one unit of each macronutrient. Linear regression analysis was used to estimate weight change for the iso-energetic increase (↑) of 1unit of percentage of energy from one macronutrient at the expense of another (↓). Models were adjusted for baseline age (continuous), sex (except sex strata), physical activity (low, moderate and high), smoking (former and current smoker/never smoked), education le vel (> 12 and ≤ 12 years of education), baseline BMI and energy intake