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Table 4 Adjusted waist circumference change for iso-energetic replacement of macronutrients

From: The association of dietary macronutrients with anthropometric changes, using iso-energetic substitution models: Tehran lipid and glucose study

Type of macronutrient Substitution

All

Men

Women

β

P-value

β

P-value

β

P-value

Carbohydrate ↑

 Fat ↓

−0.01

0.49

−0.05

0.80

−0.01

0.68

 Protein ↓

−0.01

0.53

−0.03

0.45

0.00

0.93

Carbohydrate ↑

 SFA ↓

− 0.01

0.43

− 0.03

0.24

0.01

0.73

 MUFA ↓

− 0.02

0.33

− 0.04

0.08

0.01

0.75

 PUFA ↓

−0.01

0.534

−0.02

0.29

0.01

0.65

 Protein ↓

−0.02

0.30

−0.04

0.08

0.01

0.74

Carbohydrate ↑

 Fat ↓

0.00

0.75

0.01

0.62

0.00

0.88

 Plant Protein ↓

−0.01

0.58

−0.03

0.38

0.00

0.84

 Animal Protein ↓

−0.01

0.53

−0.03

0.46

0.00

0.94

Carbohydrate ↑

 SFA ↓

0.00

0.75

−0.00

0.99

0.02

0.43

 MUFA ↓

0.00

0835

−0.02

0.37

0.02

0.50

 PUFA ↓

0.00

0.91

−0.01

0.78

0.01

0.47

 Plant Protein ↓

0.02

0.31

−0.04

0.07

0.01

0.69

 Animal Protein ↓

0.00

0.87

−0.02

0.41

0.01

0.50

Plant protein ↑

 Animal protein ↓

0.01

0.59

−0.05

0.00

0.01

0.54

 Carbohydrate ↓

−0.12

0.14

−0.05

0.00

−0.15

0.48

 Fat ↓

−0.12

0.16

−0.05

0.01

−0.17

0.31

Plant protein ↑

 Animal protein ↓

−1.01

0.00

−0.11

0.00

−0.46

0.43

 Starch ↓

−0.17

0.11

−0.07

0.00

−0.15

0.44

 Non-starch ↓

−0.10

0.00

−0.12

0.00

−0.41

0.49

 Fat ↓

−0.10

0.00

−0.12

0.00

−0.40

0.50

Plant protein ↑

 Animal protein ↓

−0.05

0.00

−0.01

0.00

−0.03

0.07

 Carbohydrate ↓

−0.05

0.00

−0.07

0.00

−0.03

0.08

 SFA ↓

−0.05

0.00

−0.03

0.68

−0.06

0.00

 MUFA ↓

−0.05

0.00

−0.06

0.00

−0.03

0.05

 PUFA ↓

−0.05

0.00

−0.07

0.00

−0.03

0.07

Plant protein ↑

 Animal protein ↓

−1.60

0.00

−0.14

0.00

−1.11

0.08

 Starch ↓

−0.11

0.32

−0.09

0.00

−0.11

0.57

 Non-starch ↓

−1.60

0.00

−0.15

0.00

−1.11

0.48

 SFA ↓

−1.54

0.00

−0.14

0.00

−1.11

0.08

 MUFA ↓

−1.57

0.00

−0.13

0.00

−1.11

0.08

 PUFA ↓

−1.61

0.00

−0.15

0.00

−1.15

0.08

  1. SFA Saturated fatty acid, MUFA Mono-unsaturated fatty acids, PUFA Poly-unsaturated fatty acids. Non-starch carbohydrates: simple sugars
  2. The percentage of energy from macronutrients divides by 5 to calculate one unit of each macronutrient. Estimating waist circumference change was calculated using linear regression analysis for the iso-energetic increase (↑) of 1 unit of percentage of energy from one macronutrient at the expense of another (↓). Models were adjusted for baseline age (continuous), sex (except sex strata), physical activity (low, moderate and high), smoking (former and current smoker/never smoked), education level (> 12 and ≤ 12 years of education), baseline waist circumference and energy intake