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Table 1 Epidemiological studies showing a link between milk consumption, insulin resistance and type 2 diabetes mellitus

From: Milk exosomal miRNAs: potential drivers of AMPK-to-mTORC1 switching in β-cell de-differentiation of type 2 diabetes mellitus

Study (R = retrospective; P = prospective)

n

Type of milk

Ref.

Dietary intervention milk vs. meat (P)

Denmark

24

Skim milk

[3]

British Women’s Heart and Health Study (R)

UK

4024

Skim, low-fat, whole milk

[4]

EPIC-Interact Study (P)

Europe

340,234

Not fermented milk

[7]

Physicians´ Health Study (P)

USA

21,660

Skim, low-fat, whole milk

[6]

Mendelian randomization study (R)

Denmark

97,881

Milk, fat-free milk

[5]

Framingham Heart Study Offspring Cohort (P) USA

2809

Whole milk

[9]

Lifelines Cohort Study (P)

Netherlands

112,086

Full-fat, skim milk

[8]