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Fig. 6 | Nutrition & Metabolism

Fig. 6

From: Retinol and vitamin A metabolites accumulate through RBP4 and STRA6 changes in a psoriasis murine model

Fig. 6

RNA sequencing of lesional and non-lesional skin in the IMQ study groups. a Venn diagram showing the number of differentially expressed genes between the different groups. b, c GO annotation of differentially expressed genes (fold change ≥2) between the lesional and non-lesional skin of groups A and B. Genes with increased expression are depicted in 6B, while genes with reduced expression are in 6C. d KEGG pathway enrichment analysis of the genes related to “retinoid metabolic process”. e Broken line graph showing the expression of retinol binding protein in IMQ lesional skin compared with non-lesional skin. The serial numbers representing the corresponding gene designations are as follows: 12903, CRABP1; 12,904, CRABP2; 19,660, CRBP2; 394,435, Ugt1a6b; 79,235, lecithin: ROL acyltransferase LRAT. “N” indicates non-lesional skin; “L” indicates lesional skin; “1 and 2” correspond to groups A and B, respectively

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