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Fig. 7 | Nutrition & Metabolism

Fig. 7

From: Trehalose itself plays a critical role on lipid metabolism: Trehalose increases jejunum cytoplasmic lipid droplets which negatively correlated with mesenteric adipocyte size in both HFD-fed trehalase KO and WT mice

Fig. 7

Effect of trehalose on lipid droplet accumulation, ApoB-100 and ApoB-48 secretion in Caco-2 cells. Caco-2 cells were treated with or without micelles and 50 mM trehalose. The cultured cells were fixed with formaldehyde, mounted and observed using a fluorescence microscope (a). The bright areas with BODIPY™ FL C16 were analyzed (b). Culture supernatants from the basal side were analyzed for ApoB-100 and ApoB-48 by western blotting (c). The relative amount of ApoB-48 with or without Tre relative to micelles (−) was summarized (d). Values are shown as means ± standard deviation (n = 3). The values indicate statistical significance (7b: p < 0.05, p < 0.01, Tukey-Kramer test). No statistical significance was observed (7d: t-test)

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