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Table 2 Composition of polyunsaturated FAs in major tissues

From: Correction to: The effect of western diet on mice brain lipid composition

  Chow [mg/g] Serum [mg/L] Brain [%] Liver [%] Retroperitoneal adipose tissue [%] Epididymal adipose tissue [%] Subcutaneous adipose tissue [%]        
  10% 60% SD HFD SD HFD SD HFD SD HFD SD HFD SD HFD
SFA 17.9 ± 0.64 136 ± 8.00 ** 1049 ± 286 1855 ± 397 ** 46.13 ± 1.06 46.82 ± 2.14 37.41 ± 0.86 38.03 ± 4.72 33.75 ± 2.46 29.73 ± 1.64 * 29.08 ± 1.53 29.28 ± 1.63 31.99 ±1.39 28.80 ±.29 *
MUFA 10.7 ± 0.12 87.9 ± 4.15 # 1164 ± 389 1289 ± 274 32.35 ± 2.64 30.99 ± 2.75 41.26 ± 2.56 39.15 ± 11.23 62.51 ± 2.16 62.06 ± 1.73 66.86 ± 1.29 62.58 ± 1.43 * 64.19 ± 1.44 63.03 ±2.17
16:2 n-6 0.067 ± 0.003 0.51 ± 0.02# 0.04 ± 0.06 0.40 ± 0.17** 0.01 ± 0.00 0.01 ± 0.01 0.003 ± 0.000 0.020 ± 0.010* 0.01 ± 0.00 0.01 ± 0.01 0.01 ± 0.00 0.01 ± 0.00* 0.003 ± 0.000 0.02 ±0.01#
LA 2.04 ± 0.04 18.6 ± 0.70# 356 ± 29.1 915 ± 114# 0.38 ± 0.08 0.72 ± 0.08# 6.40 ± 0.46 11.56 ± 2.34* 3.02 ± 0.28 7.46 ± 0.10# 3.42 ± 0.51 7.51 ± 0.31# 3.16 ± 0.17 7.51 ± 0.15#
20:2 n-6 0.058 ± 0.009 0.57 ± 0.07** 3.78 ± 0.63 9.22 ± 2.37** 0.08 ± 0.02 0.15 ± 0.03* 0.09 ± 0.01 0.17 ± 0.05* 0.07 ± 0.01 0.14 ± 0.03# 0.05 ± 0.01 0.11 ± 0.02# 0.05 ± 0.01 0.11 ± 0.02#
DGLA 0.012 ± 0.0002 0.11 ± 0.01** 32.4 ± 6.83 36.0 ± 16.2 0.35 ± 0.04 0.38 ± 0.01 1.35 ± 0.11 0.65 ± 0.17# 0.08 ± 0.02 0.06 ± 0.00* 0.05 ± 0.01 0.03 ± 0.02* 0.07 ± 0.01 0.04 ± 0.01*
ARA 0.037 ± 0.004 0.36 ± 0.01# 152 ± 37.4 330 ± 59.2# 7.93 ± 0.61 8.11 ± 0.64 8.19 ± 0.87 6.28 ± 2.83 0.10 ± 0.03 0.10 ± 0.02 0.06 ± 0.02 0.04 ± 0.03 0.11 ± 0.02 0.07 ± 0.02*
AdA 0.008 ± 0.002 0.11 ± 0.02* 1.48 ± 0.35 2.81 ± 0.60# 2.06 ± 0.25 2.01 ± 0.25 0.14 ± 0.02 0.17 ± 0.05 0.02 ± 0.01 0.01 ± 0.00* 0.01 ± 0.01 0.01 ± 0.00 0.01 ± 0.01 0.01 ± 0.00
PUFA n-6 2.16 ± 0.03 19.7 ± 0.64 # 552 ± 63.9 1295 ± 105 # 11.22 ± 0.96 11.52 ± 0.64 16.62 ± 1.38 18.93 ± 5.24 3.30 ± 0.32 7.79 ± 0.09 # 3.61 ± 0.53 7.72 ± 0.23 # 3.42 ± 0.18 7.77 ± 0.19 #
ALA 0.005 ± 0.002 0.049 ± 0.002# 5.74 ± 2.18 9.97 ± 2.55* 0.02 ± 0.01 0.02 ± 0.01 0.10 ± 0.03 0.18 ± 0.06* 0.01 ± 0.01 0.01 ± 0.01 0.01 ± 0.00 0.01 ± 0.01 0.01 ± 0.01 0.01 ± 0.00
ETA 0.002 ± 0.001 0.01 ± 0.01 2.87 ± 0.56 3.44 ± 0.89 0.06 ± 0.01 0.03 ± 0.01* 0.01 ± 0.00 0.01 ± 0.00 0.01 ± 0.00 0.01 ± 0.01 0.01 ± 0.00 0.01 ± 0.00
EPA 0.008 ± 0.002 0.074 ± 0.004# 42.9 ± 11.7 20.1 ± 2.77** 0.33 ± 0.03 0.15 ± 0.02 # 1.71 ± 0.12 0.31 ± 0.11# 0.12 ± 0.02 0.03 ± 0.00# 0.13 ± 0.02 0.05 ± 0.04# 0.12 ± 0.02 0.02 ± 0.01#
DPA 0.016 ± 0.003 0.15 ± 0.007# 2.81 ± 0.53 7.87 ± 2.28** 0.36 ± 0.05 0.31 ± 0.06 0.23 ± 0.04 0.32 ± 0.09 0.03 ± 0.01 0.02 ± 0.01 0.02 ± 0.01 0.01 ± 0.00 0.03 ± 0.01 0.01 ± 0.00#
DHA 0.006 ± 0.003 0.06 ± 0.02 30.9 ± 8.24 72.1 ± 8.81 8.91 ± 0.57 9.71 ± 0.78 2.36 ± 0.29 2.85 ± 1.28 0.03 ± 0.01 0.01 ± 0.01* 0.02 ± 0.00 0.01 ± 0.01 0.02 ± 0.00 0.01 ± 0.00
PUFA n-3 0.04 ± 0.01 0.35 ± 0.007 # 85.2 ± 21.7 114 ± 9.01 * 9.62 ± 0.60 10.19 ± 0.79 4.46 ± 0.37 3.69 ± 1.50 0.20 ± 0.04 0.08 ± 0.01 # 0.19 ± 0.01 0.10 ± 0.06 * 0.18 ± 0.02 0.06 ± 0.02 #
  1. p-value from paired t-test: * < 0.05, # < 0.001, AdA – adrenic acid (22:4 n-6), ALA – α-linolenic acid (18:3 n-3), ARA – arachidonic acid (20:4 n-6), DGLA –dihomo-γ-linolenic acid (20:3 n-6), DHA – docosahexaenoic acid (22:6 n-3), DPA – docosapentaenoic acid (22:5 n-3), EPA – eicosapentaenoic acid (20:5 n-3), ETA – eicosatetraenoic acid (20:4 n-3), LA – linoleic acid (18:2 n-6), MUFA – monounsaturated fatty acids, PUFA – polyunsaturated fatty acids, SFA – saturated fatty acid
  2. Boldface, major groups of fatty acid