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Fig. 4 | Nutrition & Metabolism

Fig. 4

From: Resveratrol promotes osteoblastic differentiation in a rat model of postmenopausal osteoporosis by regulating autophagy

Fig. 4

The autophagy modulation in cultured osteoblasts and osteoclasts with resveratrol stimulation. The cells were cultured in a differentiation medium and were stimulated with resveratrol. After differentiation, autophagy was inhibited or activated. The protein levels of p62, LC3I/LC3II, atg5, atg7, and atg12 were then measured by Western blotting in the (a, b) osteoblasts and (c, d) osteoclasts; e The fluorescence intensity of LC3 was measured in each group. LC3, protein microtubule-associated protein 1 light chain-3; atg, autophagy related gene. The data were shown as the mean ± SD (n = 3). Compared to the Sham group, *p < 0.05, **p < 0.01, ***p < 0.001; Compared to the OVX group, # p < 0.05, ## p < 0.01, ### p < 0.001

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