Table 3 KEGG pathways of differentially expressed proteins

1

Energy metabolism

00190

Oxidative phosphorylation

11

1

2

Carbohydrate metabolism

01200

Carbon metabolism

8

2

00030

Pentose phosphate pathway

4

0

00040

Pentose and glucuronate interconversions

4

1

00051

Fructose and mannose metabolism

4

1

00010

Glycolysis / Gluconeogenesis

3

0

00052

Galactose metabolism

2

1

00520

Amino sugar and nucleotide sugar metabolism

2

1

00620

Pyruvate metabolism

2

1

00630

Glyoxylate and dicarboxylate metabolism

2

1

3

Amino acid metabolism

01230

Biosynthesis of amino acids

5

1

00260

Glycine, serin vitamin e and threonine metabolism

5

1

00340

Histidine metabolism

5

0

00350

Tyrosine metabolism

3

0

00250

Alanine, aspartate and glutamate metabolism

3

1

00270

Cysteine and methionine metabolism

3

0

00220

Arginine biosynthesis

2

0

4

Lipid metabolism

00590

Arachidonic acid metabolism

2

0

00561

Glycerolipid metabolism

2

1

00140

Steroid hormone biosynthesis

2

0

5

Metabolism of cofactors and vitamins

00790

Folate biosynthesis

4

1

00760

Nicotinate and nicotinamide metabolism

2

1

00830

Retinol metabolism

2

0

6

Xenobiotics biodegradation and metabolism

00982

Drug metabolism - cytochrome P450

3

1

00980

Metabolism of xenobiotics by cytochrome P450

3

0

00983

Drug metabolism - other enzymes

2

0

7

Nucleotide metabolism

00240

Pyrimidine metabolism

2

0

8

Signal transduction

04020

Calcium signaling pathway

5

1

04152

AMPK signaling pathway

3

0

04151

PI3K-Akt signaling pathway

2

1

9

Nervous system

04723

Retrograde endocannabinoid signaling

10

0

10

Neurodegenerative diseases

05012

Parkinson’s disease

11

1

05016

Huntington’s disease

11

1

05010

Alzheimer’s disease

10

0

11

Endocrine system

04910

Insulin signaling pathway

6

0

04922

Glucagon signaling pathway

5

0

12

Endocrine and metabolic diseases

04932

Non-alcoholic fatty liver disease (NAFLD)

10

0

13

Transport and catabolism

04142

Lysosome

5

5

04144

Endocytosis

2

0

04145

Phagosome

2

2

14

Cancers

05204

Chemical carcinogenesis

3

0

05205

Proteoglycans in cancer

2

1

05200

Pathways in cancer

2

0

15

Cell growth and death

04114

Oocyte meiosis

2

1

04110

Cell cycle

2

1

04217

Necroptosis

2

2

16

Cell motility

04810

Regulation of actin cytoskeleton

2

1

17

Immune system

04612

Antigen processing and presentation

2

2

04621

NOD-like receptor signaling pathway

2

2

04610

Complement and coagulation cascades

2

2

18

Infectious diseases

05120

Epithelial cell signaling in Helicobacter pylori infection

2

1

19

Digestive system

04976

Bile secretion

2

0

20

Excretory system

04966

Collecting duct acid secretion

2

1