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Table 2 Association of lipid profile and hs-CRP levels in the second trimestera

From: Vitamin D status affects the relationship between lipid profile and high-sensitivity C-reactive protein

Groups n Hs-CRP (mg/L) level
Mean ± SD Adjustedβ (95%CI)b P
TC status
 <P25 615 3.26 ± 2.18 0.040(0.009,0.071) 0.011
 P25 ~ P75 1238 2.89 ± 1.98 Refc1  
  ≥ P75 626 3.13 ± 2.12 0.043(0.012,0.074) 0.006
TG status
 <P25 633 2.49 ± 1.88 -0.077(−0.108,-0.047) <0.001
 P25 ~ P75 1230 3.05 ± 2.01 Refc2  
  ≥ P75 616 3.59 ± 2.23 0.040(0.010,0.070) 0.010
HDL-C status
 <P25 599 3.27 ± 2.13 0.018(−0.013,0.049) 0.256
 P25 ~ P75 1271 3.02 ± 2.07 Refc3  
  ≥ P75 609 2.86 ± 2.00 −0.014(− 0.044,0.017) 0.388
LDL-C status
 <P25 621 3.37 ± 2.28 0.050(0.020,0.080) 0.001
 P25 ~ P75 1244 2.86 ± 1.88 Refc4  
  ≥ P75 614 3.08 ± 2.18 0.019(−0.012,0.049) 0.235
  1. a.25(OH)D 25-Hydroxyvitamin D; hs-CRP High-sensitivity C-reactive protein; TC Total cholesterol; TG Triglyceride; HDL-C High-density lipoprotein-cholesterol; LDL-C Low-density lipoprotein-cholesterol;
  2. b. Sociodemographic characteristics (maternal age, education, income, season), perinatal health status(pre-pregnancy BMI, systolic blood pressure and diastolic blood pressure), lifestyle(sedentary time, physical activities, paternal alcohol and smoking consumption, fish oil supplement, multivitamin supplement, milk intake, soy product intake and dessert intake), and 25(OH)D
  3. c. “Refc1” indicates P25 ≤ TC<P75 as a reference group; “Refc2” indicates P25 ≤ TG<P75 as a reference group; “Refc3” indicates P25 ≤ HDL-C<P75 as a reference group; “Refc4” indicates P25 ≤ LDL-C<P75 as a reference group