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Table 4 Relationship between lipid profile and hs-CRP in different levels of vitamin Da

From: Vitamin D status affects the relationship between lipid profile and high-sensitivity C-reactive protein

Groups

n(%)

Hs-CRP (mg/L) levels

Mean ± SD

Adjustedβ(95%CI)b

P

25(OH)D < 50 nmol/L

 TC<P25

435(23.2)

3.34 ± 2.27

0.038(0.001,0.074)

0.042

 P25 ≤ TC < P75

944(50.3)

2.99 ± 2.06

Refc1

 

 TC ≥ P75

496(26.5)

3.18 ± 2.19

0.041(0.005,0.076)

0.024

 TG<P25

440(23.5)

2.54 ± 1.95

−0.085(− 0.121,-0.048)

< 0.001

 P25 ≤ TG < P75

940(50.1)

3.12 ± 2.10

Refc2

 

 TG ≥ P75

495(26.4)

3.65 ± 2.26

0.048(0.014,0.083)

0.006

 HDL-C<P25

443(23.6)

3.42 ± 2.25

0.038(0.002,0.074)

0.040

 P25 ≤ HDL-C < P75

964(51.4)

3.06 ± 2.13

Refc3

 

 HDL-C ≥ P75

468(25.0)

2.97 ± 2.06

−0.002(−0.033,0.037)

0.909

 LDL-C<P25

432(23.0)

3.44 ± 2.40

0.050(0.014,0.085)

0.006

 P25 ≤ LDL-C < P75

955(50.9)

2.94 ± 1.93

Refc4

 

 LDL-C ≥ P75

488(26.1)

3.20 ± 2.28

0.025 (−0.010,0.059)

0.166

25(OH)D ≥ 50 nmol/L

 TC<P25

180(29.8)

2.96 ± 1.89

0.016(−0.042,0.074)

0.582

 P25 ≤ TC < P75

294(48.7)

2.54 ± 1.66

Refc1

 

 TC ≥ P75

130(21.5)

2.86 ± 1.81

0.058(−0.010,0.127)

0.096

 TG<P25

193(32.0)

2.38 ± 1.72

−0.063(,-0.120,-0.007)

0.029

 P25 ≤ TG < P75

290(48.0)

2.83 ± 1.71

Refc2

 

 TG ≥ P75

121(20.0)

3.07 ± 1.92

0.018 (−0.045,0.082)

0.573

 HDL-C<P25

156(25.8)

2.74 ± 1.63

−0.046(− 0.106,0.014)

0.113

 P25 ≤ HDL-C < P75

307(50.8)

2.86 ± 1.87

Refc3

 

 HDL-C ≥ P75

141(23.4)

2.46 ± 1.69

−0.058(−0.121,0.005)

0.070

 LDL-C<P25

189(31.3)

3.06 ± 1.94

0.034(−0.023,0.090)

0.240

 P25 ≤ LDL-C < P75

289(47.8)

2.57 ± 1.65

Refc4

 

 LDL-C ≥ P75

126(20.9)

2.63 ± 1.72

0.006(−0.060,0.063)

0.869

  1. a.25(OH)D 25-Hydroxyvitamin D; hs-CRP High-sensitivity C-reactive protein; TC Total cholesterol; TG Triglyceride; HDL-C High-density lipoprotein-cholesterol; LDL-C Low-density lipoprotein-cholesterol;
  2. b.Adjusted for sociodemographic characteristics (maternal age, education, income, season), perinatal health status(pre-pregnancy BMI, systolic blood pressure and diastolic blood pressure), lifestyle(sedentary time, physical activities, paternal alcohol and smoking consumption, fish oil supplement, multivitamin supplement, milk intake, soy product intake and dessert intake)
  3. c. “Refc1” indicates P25 ≤ TC<P75 as a reference group; “Refc2” indicates P25 ≤ TG<P75 as a reference group; “Refc3” indicates P25 ≤ HDL-C<P75 as a reference group; “Refc4” indicates P25 ≤ LDL-C<P75 as a reference group