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Fig. 2 | Nutrition & Metabolism

Fig. 2

From: High fat diet significantly changed the global gene expression profile involved in hepatic drug metabolism and pharmacokinetic system in mice

Fig. 2

Expression profiles of hepatic DMPK genes changed by treatment of high fat diet for 38 weeks. a Heatmap visualization. b Score plots of principal component analysis. c Volcano plots showing the significantly regulated genes. Names of genes changed by more than 2 folds with p < 0.01 were labled. The top and bottom horizontal line represent p values of 0.01 and 0.05, respectively; d Distribution of the expression levels of genes significantly changed by treatment of high fat diet for 38 weeks. Names of genes with fold change values more than 5 or with basel expression levels (FPKM) more than 1000 were labeled. Abbreviation: ND, normal diet group; HFD, high fat diet group

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Nutrition & Metabolism

ISSN: 1743-7075

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