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Fig. 3 | Nutrition & Metabolism

Fig. 3

From: High fat diet significantly changed the global gene expression profile involved in hepatic drug metabolism and pharmacokinetic system in mice

Fig. 3

Effect of high fat diet on DMPK system play an important role on its effect on the whole genome. a The percentage of genes significantly changed by high fat diet at the transcriptional level. Top: whole genome wide scale; bottom: DMPK system. b Distribution frequency of hepatic gene expression levels at the whole genome wide (gw) scale and DMPK system scale. Mice were treated for 0 day (day 0) or 38 weeks. . c Top five HFD-repressed genes on the genome wide levelsData were presented as mean ± SEM. ***p < 0.001 checked by the student t-test. ND, normal diet group; HFD, high fat diet group

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Nutrition & Metabolism

ISSN: 1743-7075

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