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Fig. 7 | Nutrition & Metabolism

Fig. 7

From: High fat-induced inflammation in vascular endothelium can be improved by Abelmoschus esculentus and metformin via increasing the expressions of miR-146a and miR-155

Fig. 7

AE and metformin inhibit high fat-induced endothelial inflammation independent of miR-21 in PA-exposed HAECs. a, relative mRNA levels of NF-κB p65, IL-6, MCP-1 and ICAM-1 in HAECs transfected with miR-21 mimics. b, relative protein level of p-NF-κB p65 in HAECs transfected with miR-21 mimics. c, relative mRNA levels of NF-κB p65, IL-6, MCP-1 and ICAM-1 in HAECs transfected with miR-21 inhibitors. d, relative protein levels of p-NF-κB p65 in HAECs transfected with miR-21 inhibitors. Data are presented as mean ± SEM. *P < 0.05 versus BSA group. **P < 0.01 versus BSA group. n = 5 per group for HAECs study

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