Fig. 1

RES inhibited the progression of AS in vivo. Serum of mice was collected at 0th, 10th and 20th respectively and diluted by a quarter in saline and the lipids were detected according to the operating instruction of the kits. a The level of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and non-HDL-C of serum in the 0th week (n = 8). b The level of TC, TG, LDL-C, HDL-C, and non-HDL-C in the 10th week (n = 8). c The level of TC, TG, LDL-C, HDL-C, and non-HDL-C in the 20th week (n = 8). d Mice were killed at the end of the 20th week and the hearts were preserved. The pathologic condition of the coronary artery was analyzed by H&E. e The aortas were separated from the aortic arch to the left and right common iliac artery and were stained by Oil Red O. f The areas of aortic plaque were measured by MapInfo 7.0 (n = 5). Data are represented with mean ± SD, #P < 0.05, ##P < 0.01, ###P < 0.001 versus the control group; *P < 0.05, **P < 0.01 versus the HFD + LPS group