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Table 1 Differentially upregulated genes in the model group and the control group with Log2FC ≥ 2 and P < 0.05

From: High-trans fatty acid and high-sugar diets can cause mice with non-alcoholic steatohepatitis with liver fibrosis and potential pathogenesis

Gene name

Gene description

Con

(Mean)

HFHC

(Mean)

FC (HFHC/Con)

Log2FC

(HFHC/Con)

Padjust

Regulate

Sprr1a

Small Proline-rich Protein 1A

0.00

4.59

431.01

8.75

0.0132

up

Cyp2b10

Cytochrome P450, family 2, subfamily b, polypeptide 10

0.10

25.61

274.92

8.10

0.0163

up

Cidea

Cell death-inducing DNA fragmentation factor, alpha subunit-like effector A

0.22

46.42

217.00

7.76

0.0001

up

Mas1

MAS1 oncogene

0.00

0.57

118.42

6.89

0.0156

up

Xlr4a

X-linked lymphocyte-regulated 4A

0.02

3.93

82.35

6.36

0.0330

up

Chil1

Chitinase-like 1

0.03

1.22

79.61

6.31

0.0043

up

Ttc39aos1

Ttc39a opposite strand RNA 1

0.00

1.46

67.28

6.07

0.0409

up

Cyp2b9

Cytochrome P450, family 2, subfamily b, polypeptide 9

1.56

123.01

62.17

5.96

0.0044

up

Prtn3

Proteinase 3

0.00

0.78

59.71

5.90

0.0444

up

Cyp2b13

Cytochrome P450, family 2, subfamily b, polypeptide 13

0.03

1.66

56.33

5.82

0.0103

up

Cfd

Complement factor D (adipsin)

0.23

12.86

52.08

5.70

0.0015

up

Orm3

Orosomucoid 3

0.27

7.06

25.29

4.66

0.0082

up

Nat8f7

N-acetyltransferase 8 (GCN5-related) family member 7

0.06

2.18

25.21

4.66

0.0184

up

Pls1

Plastin 1 (I-isoform)

0.14

0.69

21.32

4.41

0.0161

up

Ciart

Circadian associated repressor of transcription

0.27

5.84

20.40

4.35

0.0186

up