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Table 2 Differentially downregulated genes in the model group and the control group with Log2FC ≤ − 2 and P < 0.05

From: High-trans fatty acid and high-sugar diets can cause mice with non-alcoholic steatohepatitis with liver fibrosis and potential pathogenesis

Gene nameGene descriptionCon
(Mean)
HFHC
(Mean)
FC (HFHC/Con)Log2FC
(HFHC/Con)
PadjustRegulate
Adra2aAdrenergic receptor, alpha 2a0.470.020.04−4.700.0240Down
Serpina1eSerine (or cysteine) peptidase inhibitor, clade A, member 1E2355.3094.320.04−4.510.0052Down
LeprLeptin receptor7.010.540.06−4.040.0043Down
Cspg5Chondroitin sulfate Proteoglycan 51.110.070.06−3.960.0046Down
EnhoEnergy homeostasis associated13.421.120.09−3.520.0025Down
Slc30a3Solute carrier family 30 (zinc transporter), member 30.940.080.09−3.490.0051Down
Unc79Unc-79 homolog (C. elegans)1.150.140.13−3.000.0181Down
Gtpbp4-Ps1GTP binding Protein 4, Pseudogene 154.765.160.13−2.970.0083Down
Pitx3Paired-like homeodomain transcription factor 36.660.520.14−2.870.0033Down
Slc13a5Solute carrier family 13 (sodium-dependent citrate transporter), member 51.250.200.14−2.860.0149Down
Fam198aFamily with sequence similarity 198, member A5.430.780.14−2.800.0052Down
Pdk4Pyruvate dehydrogenase kinase, isoenzyme 433.335.430.15−2.740.0041Down
AsnsAsparagine synthetase1.170.400.16−2.680.0161Down
PPP1r3gProtein phosphatase 1, regulatory (inhibitor) subunit 3G2.540.410.16−2.660.0181Down
FstFollistatin1.470.240.17−2.600.0056Down