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Table 1 Body weight (wt.), white adipose tissue (WAT) wt., dietary intake, liver wt., and liver TG levels in the CON and HFD groups fed different levels of vitamin D1

From: Effects of high fat diet-induced obesity on vitamin D metabolism and tissue distribution in vitamin D deficient or supplemented mice

 

CON

HFD

P-value

 

LVd

(n = 9)

CVd

(n = 11)

HVd

(n = 8)

LVd

(n = 9)

CVd

(n = 11)

HVd

(n = 8)

Fat amount

Vitamin D content

Interaction

Body wt. at 0 wk. (g)

22.6 ± 0.4

23.1 ± 0.4

23.2 ± 0.2

22.7 ± 0.3

22.6 ± 0.2

22.7 ± 0.7

0.24

0.56

0.49

Body wt. at 13 wk. (g)

35.8 ± 1.0a

35.0 ± 0.4a

34.5 ± 1.1a

49.5 ± 0.7c

49.5 ± 0.9c

46.7 ± 0.8b

<  0.001

0.06

0.42

WAT wt2 (g)

2.91 ± 0.31a

2.74 ± 0.22a

2.64 ± 0.29a

5.59 ± 0.09b

5.90 ± 0.11b

5.70 ± 0.21b

<  0.001

0.79

0.50

Daily food intake (g/day)

2.96 ± 0.04

2.92 ± 0.05

2.98 ± 0.04

3.03 ± 0.05

3.11 ± 0.11

2.80 ± 0.05

0.66

0.18

0.036

Liver wt./body wt.

(%)

3.23 ± 0.14a

3.41 ± 0.14a

3.34 ± 0.09a

5.24 ± 0.13c

4.74 ± 0.23bc

4.37 ± 0.29b

<  0.001

0.16

0.038

Liver TG levels

(mg/g tissue)

57.2 ± 5.0a

54.6 ± 8.7a

63.6 ± 6.4a

138.3 ± 10.1b

127.7 ± 12.9b

111.7 ± 12.8b

<  0.001

0.62

0.28

  1. 1 Two-way ANOVA was used to determine the significant effects of fat amount and vitamin D content, and an interaction. abDifferent superscripts indicate significant difference (P <  0.05) by Fisher’s LSD multiple comparison test. Data are presented as means ± SEMs. 2White adipose tissue weight included epididymal, subcutaneous, retroperitoneum, and perinephric fats. CON 10% kcal fat diet, HFD 45% kcal fat diet; LVd Low vitamin D, CVd Control vitamin D, HVd High vitamin D