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Table 1 Body weight (wt.), white adipose tissue (WAT) wt., dietary intake, liver wt., and liver TG levels in the CON and HFD groups fed different levels of vitamin D1

From: Effects of high fat diet-induced obesity on vitamin D metabolism and tissue distribution in vitamin D deficient or supplemented mice

  CON HFD P-value
  LVd
(n = 9)
CVd
(n = 11)
HVd
(n = 8)
LVd
(n = 9)
CVd
(n = 11)
HVd
(n = 8)
Fat amount Vitamin D content Interaction
Body wt. at 0 wk. (g) 22.6 ± 0.4 23.1 ± 0.4 23.2 ± 0.2 22.7 ± 0.3 22.6 ± 0.2 22.7 ± 0.7 0.24 0.56 0.49
Body wt. at 13 wk. (g) 35.8 ± 1.0a 35.0 ± 0.4a 34.5 ± 1.1a 49.5 ± 0.7c 49.5 ± 0.9c 46.7 ± 0.8b <  0.001 0.06 0.42
WAT wt2 (g) 2.91 ± 0.31a 2.74 ± 0.22a 2.64 ± 0.29a 5.59 ± 0.09b 5.90 ± 0.11b 5.70 ± 0.21b <  0.001 0.79 0.50
Daily food intake (g/day) 2.96 ± 0.04 2.92 ± 0.05 2.98 ± 0.04 3.03 ± 0.05 3.11 ± 0.11 2.80 ± 0.05 0.66 0.18 0.036
Liver wt./body wt.
(%)
3.23 ± 0.14a 3.41 ± 0.14a 3.34 ± 0.09a 5.24 ± 0.13c 4.74 ± 0.23bc 4.37 ± 0.29b <  0.001 0.16 0.038
Liver TG levels
(mg/g tissue)
57.2 ± 5.0a 54.6 ± 8.7a 63.6 ± 6.4a 138.3 ± 10.1b 127.7 ± 12.9b 111.7 ± 12.8b <  0.001 0.62 0.28
  1. 1 Two-way ANOVA was used to determine the significant effects of fat amount and vitamin D content, and an interaction. abDifferent superscripts indicate significant difference (P <  0.05) by Fisher’s LSD multiple comparison test. Data are presented as means ± SEMs. 2White adipose tissue weight included epididymal, subcutaneous, retroperitoneum, and perinephric fats. CON 10% kcal fat diet, HFD 45% kcal fat diet; LVd Low vitamin D, CVd Control vitamin D, HVd High vitamin D