Skip to main content

Table 3 25(OH)D3 levels and total amount in liver and epididymal adipose tissue1,2

From: Effects of high fat diet-induced obesity on vitamin D metabolism and tissue distribution in vitamin D deficient or supplemented mice

   CVd HVd P-value
   CON
(n = 7)
HFD
(n = 7)
CON
(n = 7)
HFD
(n = 7)
Fat amount Vitamin D content Interaction
Liver 25(OH)D3levels
(ng/g tissue)
7.47 ± 0.43a 8.24 ± 0.67a 41.9 ± 3.5c 27.0 ± 3.0b 0.004 <  0.001 0.002
Total 25(OH)D3amount (ng) 8.65 ± 0.88a 18.94 ± 1.82a 47.8 ± 4.3b 53.5 ± 6.2b 0.052 < 0.001 0.552
Epididymal adipose tissue 25(OH)D3levels
(ng/g tissue)
3.43 ± 0.43 a 8.03 ± 1.52 a 18.1 ± 2.2 b 19.5 ± 2.1 b 0.089 < 0.001 0.364
Total 25(OH)D3amount (ng) 4.41 ± 0.77a 12.5 ± 2.1b 22.4 ± 3.0c 35.9 ± 3.9d 0.001 < 0.001 0.334
  1. 1Two-way ANOVA was used to determine the significant effects of fat amount and vitamin D content, and an interaction. abDifferent superscripts indicate significant difference (P < 0.05) by Fisher’s LSD multiple comparison test. Data are presented as means ± SEMs.2CON 10% kcal fat diet, HFD 45% kcal fat diet, CVd Control vitamin D, HVd High vitamin D