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Fig. 4 | Nutrition & Metabolism

Fig. 4

From: TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter

Fig. 4

The mRNA of the fatty acid synthesis key genes in the liver of TET1-KO mice and WT mice and the L02 and HepG2 cells transfected with siRNA were detected by Q-PCR and normalized to β-actin (a,b,c). The mRNA of the fatty acid uptake key genes in the liver of TET1-KO mice and WT mice and the L02 and HepG2 cells transfected with siRNA were detected by Q-PCR and normalized to β-actin (d,e,f). After transfection of siTET1 and the control group, the cells were cultured in MEM medium containing 10% regular Serum (Regular Serum Condition; RSC) or Lipoprotein Depleted Serum (Lipoprotein Depleted Serum Condition; LDSC), and the intracellular TG content was measured (g,h)

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