Endogenous asymmetric dimethylarginine accumulation contributes to the suppression of myocardial mitochondrial biogenesis in type 2 diabetic rats

Table 3 Changes in blood glucose, plasma insulin, ISI and serum lipid profiles in T2DM rats

Groups	FBG (mmol/L)	FIns (mU/L)	ISI (×10⁻³)	TG (mmol/L)	TC (mmol/L)	LDL-C (mmol/L)	HDL-C (mmol/L)
Control	7.00 ± 0.28	33.17 ± 4.01	4.80 ± 0.69	0.60 ± 0.02	1.25 ± 0.17	0.67 ± 0.11	0.47 ± 0.03
T2DM	20.74 ± 2.32^**	68.73 ± 5.33^**	0.83 ± 0.14^**	2.98 ± 0.19^**	3.13 ± 0.43^**	2.64 ± 0.16^**	0.34 ± 0.02^**

Levels of fasting blood glucose (FBG), fasting plasma insulin (FIns) and lipid profiles in serum including triglyceride (TG), total cholesterol (TC), low density lipoprotein-cholesterol (LDL-C) and high density lipoprotein-cholesterol (HDL-C) were assayed spectrophotometrically with respective commercial kits in control and type 2 diabetic (T2DM) rats. Insulin sensitivity index (ISI) was calculated with FBG and FIns (ISI = 1/FBG × FIns). Data are expressed as mean ± S.E.M.; n = 5. **P < 0.01 vs Control

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