|
Groups
|
FBG
(mmol/L)
|
FIns
(mU/L)
|
ISI
(×10−3)
|
TG
(mmol/L)
|
TC
(mmol/L)
|
LDL-C
(mmol/L)
|
HDL-C
(mmol/L)
|
|---|
|
Control
|
7.00 ± 0.28
|
33.17 ± 4.01
|
4.80 ± 0.69
|
0.60 ± 0.02
|
1.25 ± 0.17
|
0.67 ± 0.11
|
0.47 ± 0.03
|
|
T2DM
|
20.74 ± 2.32**
|
68.73 ± 5.33**
|
0.83 ± 0.14**
|
2.98 ± 0.19**
|
3.13 ± 0.43**
|
2.64 ± 0.16**
|
0.34 ± 0.02**
|
- Levels of fasting blood glucose (FBG), fasting plasma insulin (FIns) and lipid profiles in serum including triglyceride (TG), total cholesterol (TC), low density lipoprotein-cholesterol (LDL-C) and high density lipoprotein-cholesterol (HDL-C) were assayed spectrophotometrically with respective commercial kits in control and type 2 diabetic (T2DM) rats. Insulin sensitivity index (ISI) was calculated with FBG and FIns (ISI = 1/FBG × FIns). Data are expressed as mean ± S.E.M.; n = 5. **P < 0.01 vs Control