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Table 4 Cardiac dysfunction measured by echocardiography in T2DM rats

From: Endogenous asymmetric dimethylarginine accumulation contributes to the suppression of myocardial mitochondrial biogenesis in type 2 diabetic rats

Parameters Control Diabetes
HMI (mg/g) 2.26 ± 0.09 2.84 ± 0.13**
HR (bpm) 379.31 ± 2.34 341.13 ± 22.43
CO (ml/min) 46.44 ± 3.29 43.74 ± 3.01
EF (%) 84.80 ± 2.58 54.05 ± 2.87**
FS (%) 55.19 ± 3.75 35.13 ± 0.76**
IVRT (ms) 22.67 ± 0.87 35.30 ± 1.37**
E/A (ratio) 1.66 ± 0.04 0.72 ± 0.04**
ESV (μl) 20.41 ± 4.16 105.86 ± 9.72**
EDV (μl) 140.34 ± 9.41 228.80 ± 9.54**
LVIDs (mm) 2.30 ± 0.18 4.37 ± 0.11**
LVIDd (mm) 5.16 ± 0.19 6.72 ± 0.16**
LVPWs (mm) 3.17 ± 0.13 3.38 ± 0.14
LVPWd (mm) 2.30 ± 0.13 2.32 ± 0.08
IVSs (mm) 2.99 ± 0.11 3.25 ± 0.07
IVSd (mm) 2.05 ± 0.06 2.22 ± 0.07
  1. Data are expressed as mean ± S.E.M., n = 5, **P < 0.01 vs Control
  2. T2DM Type 2 diabetes mellitus, HMI Heart mass index, HR Heart rate, CO Cardiac output, EF Ejection fraction, FS Fractional shortening, IVRT Isovolumic relaxation time, E/A The ratio of early (E) to late (A) left ventricular filling velocities, ESV or EDV End-systolic or end-diastolic volume, LVIDs or LVIDd Left ventricle internal diameter at end-systole or end-diastole, LVPWs or LVPWd Left ventricle posterior wall thickness at end-systole or end-diastole, IVSs or IVSd Interventricular septum thickness at end-systole or end-diastole