Table 1 Candidate biomarkers of T2DM suggested by KEGG pathway enrichment analysis
Pathogenesis (suggested by KEGG pathways) | Candidate biomarkers of T2DM | |
|---|---|---|
Up-regulated proteins | Down-regulated proteins | |
Oxidative Stress | Â | ceruloplasmin |
| Â | extracellular superoxide dismutase [Cu-Zn] | |
| Â | glutathione peroxidase 6 | |
Insulin Resistance | glycogen phosphorylase, liver form | insulin-like growth factor 1, isoform CRA_b |
60 kDa heat shock protein, mitochondrial |  | |
Glycan Biosynthesis and Metabolism | glyceraldehyde-3-phosphate dehydrogenase | Â |
4-trimethylaminobutyraldehyde dehydrogenase | Â | |
Lipid Metabolism | apolipoprotein C-I | apolipoprotein M |
apolipoprotein C-II (Predicted) | very low-density lipoprotein receptor | |
apolipoprotein C-IV | Â | |