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Table 1 Candidate biomarkers of T2DM suggested by KEGG pathway enrichment analysis

From: Metalloproteins and apolipoprotein C: candidate plasma biomarkers of T2DM screened by comparative proteomics and lipidomics in ZDF rats

Pathogenesis
(suggested by KEGG pathways)
Candidate biomarkers of T2DM
Up-regulated proteins Down-regulated proteins
Oxidative Stress   ceruloplasmin
  extracellular superoxide dismutase [Cu-Zn]
  glutathione peroxidase 6
Insulin Resistance glycogen phosphorylase, liver form insulin-like growth factor 1, isoform CRA_b
60 kDa heat shock protein, mitochondrial  
Glycan Biosynthesis and Metabolism glyceraldehyde-3-phosphate dehydrogenase  
4-trimethylaminobutyraldehyde dehydrogenase  
Lipid Metabolism apolipoprotein C-I apolipoprotein M
apolipoprotein C-II (Predicted) very low-density lipoprotein receptor
apolipoprotein C-IV