Skip to main content

Table 2 Association of urinary iodine with elevation of UACR and reduction of eGFR

From: Iodine nutrition status and its association with microvascular complications in urban dwellers with type 2 diabetes

Urinary iodine

Adequate

Low

More than adequate

Excessive

High UACR

 Prevalence,%

24.4

27.5

24.6

24.2

 Odds Ratio

  Model 1

1.0 (Ref.)

1.17 (1.02–1.36)*

1.01 (0.80–1.28)

0.99 (0.74–1.32)

  Model 2

1.0 (Ref.)

1.17 (1.01–1.38)*

0.95 (0.73–1.23)

0.97 (0.70–1.34)

Reduced eGFR

 Prevalence, %

4.9

6.5

3.3

7.8

 Odds Ratio

  Model 1

1.0 (Ref.)

1.35 (1.03–1.79)*

0.67 (0.38–1.16)

1.67 (1.03–2.70)*

  Model 2

1.0 (Ref.)

1.17 (0.86–1.58)

0.67 (0.36–1.22)

1.48 (0.85–2.58)

DKD

 Prevalence, %

26.2

29.8

26.2

28.5

 Odds Ratio

  Model 1

1.0 (Ref.)

1.19 (1.04–1.37)*

1.00 (0.79–1.26)

1.12 (0.85–1.48)

  Model 2

1.0 (Ref.)

1.17 (1.01–1.37)*

0.93 (0.72–1.21)

1.13 (0.83–1.54)

  1. Data are expressed as odds ratios (95%CI). Logistic regression analyses were used for the association of urinary iodine with elevation of UACR, reduction of eGFR and DKD. *P < 0.05
  2. Model 1 was unadjusted
  3. Model 2 was adjusted for age, sex, education, current smokers, BMI, HbA1C, duration of diabetes, dyslipidemia, TSH and FT4
  4. High UACR was defined as UACR ≥30 mg/g, reduced eGFR as eGFR <60 ml/min/1.73 m2, and DKD as UACR > 30 mg/g or eGFR < 60 mL/min/1.73 m2
  5. Urinary iodine concentrations: low, < 100 μg/L; adequate, 100 to < 200 μg/L; more than adequate, 200 to < 300 μg/L; excessive, ≥300 μg/L