Variates | Total (n = 1089) | Development cohort (n = 762) | Validation cohort (n = 327) | P |
---|---|---|---|---|
Age (years)a | 56.4 ± 11.1 | 56.5 ± 15.2 | 56.1 ± 15.0 | 0.640 |
Male, n (%) | 554 (50.8) | 382 (50.1) | 172 (52.4) | 0.509 |
BMI (kg/m2) | 23.2 ± 3.8 | 23.3 ± 3.8 | 23.0 ± 4.0 | 0.146 |
DM, n (%) | 424 (38.9) | 297 (39.0) | 127 (38.7) | 0.946 |
CVD, n (%) | 431 (39.5) | 293 (38.5) | 138 (42.1) | 0.280 |
Height (cm) | 164.3 ± 8.5 | 164.3 ± 8.5 | 164.4 ± 8.7 | 0.867 |
Weight (kg) | 62.1 ± 12.5 | 62.1 ± 12.0 | 62.1 ± 13.5 | 0.947 |
Handgrip strength (kg) | 22.0 ± 10.9 | 22.0 ± 10.9 | 21.8 ± 10.7 | 0.664 |
Lean body mass (kg) | 42.6 ± 8.5 | 42.6 ± 9.4 | 42.7 ± 8.9 | 0.917 |
Lean mass index (kg/m2) | 15.6 ± 1.9 | 15.6 ± 1.9 | 15.6 ± 2.0 | 0.900 |
Laboratory and nutrition data | Â | Â | Â | Â |
 Serum albumin (g/L) | 35.6 ± 4.6 | 35.4 ± 4.7 | 35.8 ± 4.4 | 0.188 |
 Hemoglobin (g/L) | 101.8 ± 15.8 | 101.7 ± 16.0 | 102.2 ± 15.4 | 0.677 |
 Hs-CRP (mg/L) | 2.2 (0.8, 6.1) | 2.2 (0.9, 6.1) | 2.2 (0.7, 6.1) | 0.994 |
 Urea nitrogen (mmol/L) | 23.0 ± 6.3 | 23.0 ± 6.5 | 22.9 ± 6.0 | 0.959 |
 Serum creatinine (umol/L) | 712.6 ± 247.5 | 710.7 ± 247.3 | 717.0 ± 248.3 | 0.700 |
 Serum calcium (mmol/L) | 2.20 ± 0.2 | 2.2 ± 0.2 | 2.2 ± 0.2 | 0.131 |
 Serum phosphorus (mmol/L) | 1.6 ± 0.4 | 1.6 ± 0.4 | 1.6 ± 0.4 | 0.949 |
 Serum sodium (mmol/L) | 139.2 ± 2.6 | 139.1 ± 2.6 | 139.2 ± 2.6 | 0.531 |
 Serum potassium (mmol/L) | 4.4 ± 0.6 | 4.4 ± 0.6 | 4.4 ± 0.6 | 0.687 |
 HDL-cholesterol (mmol/L) | 1.1 ± 0.3 | 1.1 ± 0.3 | 1.1 ± 0.4 | 0.299 |
 LDL-cholesterol (mmol/L) | 2.6 ± 0.8 | 2.6 ± 0.8 | 2.6 ± 0.8 | 0.874 |
 Total cholesterol (mmol/L) | 4.8 ± 1.2 | 4.9 ± 1.3 | 4.8 ± 1.1 | 0.244 |
 Triglycerides (mmol/L) | 1.5 (1.1, 2.1) | 1.5 (1.1, 2.0) | 1.5 (1.2, 2.2) | 0.239 |
 iPTH (pg/mL) | 170.0 (82.3, 329.5) | 178.9 (84.0, 336.7) | 158.6 (76.8, 313.3) | 0.246 |
 Total CCr (L/w/1.73 m2) | 69.3 ± 28.8 | 68.8 ± 28.4 | 70.4 ± 29.6 | 0.432 |
 Total Kt/V | 1.9 ± 0.6 | 1.9 ± 0.6 | 1.9 ± 0.6 | 0.646 |
 RRF (ml/min) | 3.2 (1.7, 5.4) | 3.2 (1.8, 5.1) | 3.5 (1.5, 5.8) | 0.345 |