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Table 1 Characteristics of participants according to quintile of Akkermansia abundance (n = 10,534)

From: Gut bacteria Akkermansia is associated with reduced risk of obesity: evidence from the American Gut Project

Characteristics a Q1 Q2 Q3 Q4 Q5 P for trend b
0–0.003 0.003–0.022 0.022–0.023 0.024–1.40 1.4–49.8  
n 2107 2107 2106 2107 2107  
Age (years) 50.4 ± 15 50.5 ± 14.8 52.5 ± 14.5 53.4 ± 14.7 56.2 ± 14.3  < 0.001
Sex, male, n (%) 988 (46.9) 1079 (51.2) 1024 (48.6) 912 (43.3) 843(40.0)  < 0.001
BMI (kg/m2) 24.5 ± 5.2 24.9 ± 4.9 24.7 ± 4.8 24.2 ± 4.5 24.4 ± 4.7  < 0.001
Normal, n (%) 1326 (62.9) 1274 (60.5) 1306(62.0) 1358 (64.5) 1302 (61.8)  
Overweight, n (%) 535 (25.4) 563 (26.7) 553 (26.3) 562 (26.7) 593 (28.1)  
Obesity, n (%) 246 (11.7) 270 (12.8) 247 (11.7) 187 (8.9) 212 (10.1)  
Smoking, n (%) c       0.01
Never 1915(90.9) 1919 (91.1) 1960 (93.1) 1994 (94.6) 1997 (94.8)  
Occasionally 110 (5.2) 120 (5.7) 102 (4.8) 69 (3.3) 66 (3.1)  
Regularly 68 (3.2) 49 (2.3) 37 (1.8) 32 (1.5) 30 (1.4)  
Alcohol drinking, n (%)d       0.23
Never 416 (19.7) 390 (18.5) 330 (15.7) 327 (15.5) 385 (18.2)  
Occasionally 1004 (47.7) 1032 (49.0) 1027 (48.8) 1032 (49.0) 981 (46.6)  
Regularly 668 (31.7) 669 (31.8) 740 (35.1) 729 (34.6) 727 (34.5)  
Diet, vegan, n (%) e 134 (6.4) 182 (8.6) 120 (5.7) 138 (6.5) 114 (0.54) 0.02
Country, U.K., n (%) 640 (30.3) 592 (28.1) 657 (31.2) 665 (31.6) 668 (31.7) 0.40
  1. a Data are means ± SD or n (%)
  2. b P-value was calculated after adjustment for age, sex, except for itself
  3. c, d, e Data are missing for 66, 77, 124 participants, respectively
  4. f Range of the relative abundances of Akkermansia (%)