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Table 3 Odds ratio# (95% confidence interval) of obesity before and after 40 years old

From: Gut bacteria Akkermansia is associated with reduced risk of obesity: evidence from the American Gut Project

 

Age groups (year)

20–39

40–99

BMI

23.3 ± 4.2

24.9 ± 5.0

Normal, n, (%)

1752 (74.7)

1752 (58.8)

Overweight, n, (%)

445 (19.0)

445 (28.8)

Obesity, n, (%)

149 (6.4)

149 (12.4)

Model 1a, OR (95% CI)

0.20 (0.04–0.65)***

0.78 (0.64–0.92)

Model 2b, OR (95% CI)

0.19 (0.03–0.62)***

0..77 (0.64–0.91)

  1. aModel 1 was adjusted for sex
  2. bModel 2 was additionally adjusted for diet type, smoking and alcohol drinking and country
  3. #The Obesity risk of elevating 10% abundance of Akkermansia
  4. ***OR differences between age groups were significant with P values of < 0.0001 by Mann–Whitney U-test