Characteristics
|
Total
|
Without CINb
|
CIN1
|
CIN2+c
|
P valued
|
---|
No. of participants (%)
|
2304 (100.0)
|
1503 (65.2)
|
564 (24.5)
|
237 (10.3)
| |
Age (years)
| | | | | |
< 30
|
58 (2.5)
|
36 (2.4)
|
19 (3.4)
|
3 (1.3)
| |
30–39
|
284 (12.3)
|
180 (12.0)
|
63 (11.1)
|
41 (17.3)
| |
40–49
|
711 (30.9)
|
441 (29.3)
|
175 (31.0)
|
95 (40.1)
|
0.041
|
50–59
|
970 (42.1)
|
666 (44.3)
|
231 (41.0)
|
73 (30.8)
| |
> 60
|
281 (12.2)
|
180 (12.0)
|
76 (13.5)
|
25 (10.5)
| |
Education (years)
| | | | | |
0–6
|
472 (20.5)
|
309 (20.6)
|
117 (20.7)
|
46 (19.4)
| |
7–9
|
996 (43.2)
|
630 (41.9)
|
239 (42.4)
|
127 (53.6)
|
0.047
|
> 9
|
836 (36.3)
|
564 (37.5)
|
208 (36.9)
|
64 (27.0)
| |
Yearly incomee (¥)
| | | | | |
< 10,000
|
262 (11.4)
|
173 (11.5)
|
65 (11.5)
|
24 (10.1)
| |
10,000–30,000
|
1119 (48.6)
|
738 (49.1)
|
255 (45.2)
|
126 (53.2)
|
0.763
|
> 30,000
|
923 (40.1)
|
592 (39.3)
|
244 (43.3)
|
87 (36.7)
| |
Tobacco smoking
|
49 (2.1)
|
29 (1.9)
|
12 (2.1)
|
8 (3.4)
|
0.063
|
Menopause status
|
1174 (51.0)
|
803 (53.4)
|
293 (52.0)
|
78 (32.9)
|
0.001
|
High-risk HPVf
| | | | | |
Positive
|
755 (32.8)
|
429 (28.5)
|
168 (29.8)
|
158 (66.7)
|
< 0.001
|
Negative
|
1549 (67.2)
|
1074 (71.5)
|
396 (70.2)
|
79 (33.3)
| |
Age at menarche (years)
| | | | | |
< 13
|
308 (13.4)
|
181 (12.0)
|
93 (16.5)
|
34 (14.3)
| |
13–< 15
|
739 (32.1)
|
466 (31.0)
|
180 (32.0)
|
93 (39.2)
|
0.028
|
15–< 17
|
654 (28.4)
|
452 (30.1)
|
133 (23.6)
|
69 (29.1)
| |
> 17
|
603 (26.2)
|
404 (26.9)
|
158 (28.0)
|
41 (17.3)
| |
IUDg use
|
1081 (46.9)
|
735 (48.9)
|
231 (41.0)
|
115 (48.5)
|
0.892
|
Years of IUD use (years)
| | | | | |
< 10
|
1632 (70.8)
|
1037 (69.0)
|
426 (75.5)
|
169 (71.3)
|
0.287
|
≥ 10
|
672 (29.2)
|
466 (31.0)
|
138 (24.5)
|
68 (28.7)
| |
SCJh visibility
| | | | | |
Fully visualized
|
646 (28.0)
|
382 (25.4)
|
185 (32.8)
|
79 (33.3)
|
0.114
|
Not fully visualized
|
1658 (72.0)
|
1121 (74.6)
|
379 (67.2)
|
158 (66.7)
| |
Vaginal pH
| | | | | |
< 4.5
|
514 (22.3)
|
341 (22.7)
|
106(18.8)
|
67 (28.3)
|
0.228
|
≥ 4.5
|
1790 (77.7)
|
1162 (77.3)
|
458 (81.2)
|
170 (71.7)
| |
Had gynecologic surgery
|
397 (17.2)
|
255 (17.0)
|
107 (19.0)
|
35 (14.8)
|
0.647
|
Had vaginitis
|
140 (6.1)
|
82 (5.5)
|
38 (6.7)
|
20 (8.4)
|
0.108
|
Sexual activity in menstrual period
|
56 (2.4)
|
39 (2.6)
|
9 (1.6)
|
8 (3.4)
|
0.549
|
- aData were presented as number (%) of participants
- bCIN, cervical intraepithelial neoplasia. All CIN status is by histology
- cCIN2+ included CIN 2, CIN 3 and SCC
- dP values for differences between groups were obtained from the chi-square test for categorical categoric variables
- eRepresent in terms of Chinese Renminbi (RMB)
- fHPV, human papilloma virus
- gIUD, intrauterine device
- hSCJ, squamous-columnar junction