| |
Subjects in the second trimester
|
subjects in the third trimester
|
|---|
|
GDM (n = 200)
|
NGT (n = 200)
|
P
|
GDM (n = 130)
|
NGT (n = 130)
|
P
|
|---|
|
NGF (pg/ml)
|
2.92 (2.05, 3.78)
|
1.87 (1.42, 2.43)
|
< 0.001
|
1.86 (1.33, 2.41)
|
1.97 (1.51, 2.64)
|
0.055
|
|
IL-6 (pg/ml)
|
3.69 (2.01, 7.82)
|
4.28 (2.36, 7.84)
|
0.217
|
4.32 (2.53, 9.21)
|
4.33 (2.53, 9.4)
|
0.838
|
|
Leptin (ng/ml)
|
10.74 (7.28, 13.79)
|
11.23 (7.08, 16.00)
|
0.099
|
10.33 (6.46, 13.53)
|
11.91 (7.94, 17.39)
|
0.031
|
|
IL-8 (pg/ml)
|
101.23 (42.03, 202.40)
|
126.46 (47.84, 268.77)
|
0.015
|
33.56 (17.58, 77.18)
|
34.89 (17.12, 57.27)
|
0.159
|
|
MCP-1 (pg/ml)
|
146.8 (109.86, 189.25)
|
158.37 (112.18, 211.55)
|
0.059
|
142.48 (114.32, 173.62)
|
145.73 (112.77, 185.09)
|
0.866
|
|
TNF-α (pg/ml)
|
3.33 (2.39, 4.44)
|
3.22 (2.23, 4.28)
|
0.432
|
3.94 (2.46, 5.59)
|
3.53 (2.28, 4.79)
|
0.121
|
|
IL-1β (pg/ml)
|
1.78 (1.13, 3.95)
|
2.15 (1.13, 4.45)
|
0.271
|
1.09 (1.01, 1.97)
|
1.09 (1.01, 1.49)
|
0.260
|
- Data are median (interquartile range)
- GDM gestational diabetes mellitus, NGT normal glucose tolerance, NGF nerve growth factor, IL-6 Interleukin-6, IL-8 Interleukin-8, MCP- monocyte chemoattractant protein 1, TNFα tumor necrosis factor-alpha, IL-β Interleukin-1beta
