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Table 2 Inflammatory cytokines in the second and third trimesters

From: Nerve growth factor is closely related to glucose metabolism, insulin sensitivity and insulin secretion in the second trimester: a case–control study in Chinese

  Subjects in the second trimester subjects in the third trimester
GDM (n = 200) NGT (n = 200) P GDM (n = 130) NGT (n = 130) P
NGF (pg/ml) 2.92 (2.05, 3.78) 1.87 (1.42, 2.43) < 0.001 1.86 (1.33, 2.41) 1.97 (1.51, 2.64) 0.055
IL-6 (pg/ml) 3.69 (2.01, 7.82) 4.28 (2.36, 7.84) 0.217 4.32 (2.53, 9.21) 4.33 (2.53, 9.4) 0.838
Leptin (ng/ml) 10.74 (7.28, 13.79) 11.23 (7.08, 16.00) 0.099 10.33 (6.46, 13.53) 11.91 (7.94, 17.39) 0.031
IL-8 (pg/ml) 101.23 (42.03, 202.40) 126.46 (47.84, 268.77) 0.015 33.56 (17.58, 77.18) 34.89 (17.12, 57.27) 0.159
MCP-1 (pg/ml) 146.8 (109.86, 189.25) 158.37 (112.18, 211.55) 0.059 142.48 (114.32, 173.62) 145.73 (112.77, 185.09) 0.866
TNF-α (pg/ml) 3.33 (2.39, 4.44) 3.22 (2.23, 4.28) 0.432 3.94 (2.46, 5.59) 3.53 (2.28, 4.79) 0.121
IL-1β (pg/ml) 1.78 (1.13, 3.95) 2.15 (1.13, 4.45) 0.271 1.09 (1.01, 1.97) 1.09 (1.01, 1.49) 0.260
  1. Data are median (interquartile range)
  2. GDM gestational diabetes mellitus, NGT normal glucose tolerance, NGF nerve growth factor, IL-6 Interleukin-6, IL-8 Interleukin-8, MCP- monocyte chemoattractant protein 1, TNFα tumor necrosis factor-alpha, IL-β Interleukin-1beta