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Table 3 Diet-induced changes in carbohydrates

From: Differential ketogenic diet-induced shift in CSF lipid/carbohydrate metabolome of pediatric epilepsy patients with optimal vs. no anticonvulsant response: a pilot study

  

During diet/Prediet

Compound Family

Compound

optimal response

no response

Glycolysis

1,5-anhydroglucitol

0.57**

0.47**

Glucose

0.83***

0.93

Lactate

0.96

1.05

Glycerate

1.12

0.99

Pyruvate

1.18***

1.93

Hexose Metabolism

Galactitol (dulcitol)

0.67**

0.87

Sorbose

0.71*

8.04**

Sorbitol

1.11

1.27

Fructose

1.13

1.46**

Mannose

1.52***

1.35***

Mannitol

1.66***

1.70**

Pentose Metabolism

Threitol

0.61*

0.74*

Xylitol

0.94

0.92

Ribitol

1.04

0.97

Xylose

1.12

1.04

Ribose

1.18

1.12

Ribulose

1.37*

1.16

Xylonate

1.38**

1.15

Arabitol

1.54***

1.48**

Arabinose

2.38***

1.63***

Aminosugar Metabolism

Erythronate

0.84*

0.77**

N-acetylneuraminate

0.98

0.93

Glucuronate

1.04

1.04

Advanced Glycation End-product

Erythrulose

1.3

0.58*

  1. Ratios are fold changes from during KD compared to before KD. Compounds are grouped by compound family, and by optimal response ratio within that family. Significant increases are indicated with bold, significant decreases with italics. False-discovery rates: *0.10 < q < 0.20, **0.05 < q < 0.10, ***q < 0.05