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Table 3 HOMA-IR, HOMA-S and HOMA-β indices, ACTH and corticosterone plasma concentrations in non-pre-diabetic (NPD) and pre-diabetic (PD) rats (n = 6, per group)

From: The dysregulation of the hypothalamic–pituitary–adrenal axis in diet-induced prediabetic male Sprague Dawley rats

Groups (n = 6) Plasma glucose (mmol/L) Plasma insulin (pmol/L) HOMA-IR values HOMA-S values (%) HOMA-β
values (%)
Plasma ACTH (pg/ml) Plasma corticosterone (ng/ml)
NPD 5.18 ± 0.36 22.43 ± 3.98 0.43 234.2 49.4 706.50 ± 11.35 147.20 ± 1.37
PD 5.80 ± 0.44 145.30 ± 4.73 2.75* 36.3 141.2 635.80 ± 13.84 ** 157.40 ± 1.70**
  1. Values are expressed mean ± SEM
  2. *p < 0.05; **p < 0.01, denotes comparison with NPD