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Table 3 HOMA-IR, HOMA-S and HOMA-β indices, ACTH and corticosterone plasma concentrations in non-pre-diabetic (NPD) and pre-diabetic (PD) rats (n = 6, per group)

From: The dysregulation of the hypothalamic–pituitary–adrenal axis in diet-induced prediabetic male Sprague Dawley rats

Groups (n = 6)

Plasma glucose (mmol/L)

Plasma insulin (pmol/L)

HOMA-IR values

HOMA-S values (%)

HOMA-β

values (%)

Plasma ACTH (pg/ml)

Plasma corticosterone (ng/ml)

NPD

5.18 ± 0.36

22.43 ± 3.98

0.43

234.2

49.4

706.50 ± 11.35

147.20 ± 1.37

PD

5.80 ± 0.44

145.30 ± 4.73

2.75*

36.3

141.2

635.80 ± 13.84 **

157.40 ± 1.70**

  1. Values are expressed mean ± SEM
  2. *p < 0.05; **p < 0.01, denotes comparison with NPD