Table 2 Genotypic and allelic frequencies of the two SNPs in the Han and Maonan ethnic groups [n (%)]
| SNP | Genotype | Han | Maonan | PHan versus Maonan | PHan | PMaoan | ||||
|---|---|---|---|---|---|---|---|---|---|---|
|
All (n = 1254) |
Normal (n = 662) |
HLP (n = 592) |
All (n = 1213) |
Normal (n = 577) |
HLP (n = 636) | |||||
|
SLC44A4 rs577272 A>G | A/A |
394 (31) |
215 (32) |
179 (30) |
309 (25) |
182 (32) |
127 (20) | |||
| A/G |
638 (51) |
331 (50) |
307 (52) |
602 (50) |
270 (47) |
332 (52) | ||||
| G/G |
222 (18) |
116 (18) |
106 (18) |
302 (25) |
125 (22) |
177 (28) | 1.09E−5 | 0.692 | 1.43E−5 | |
| G |
1426 (57) |
761 (57) |
665 (56) |
1220 (50) |
634 (55) |
586 (46) | ||||
| A |
1082 (43) |
563 (43) |
519 (44) |
1206 (50) |
520 (45) |
686 (54) | 3.73E−6 | 0.508 | 1.28E−5 | |
| PHWE | 0.21 | 0.58 | 0.21 | 0.82 | 0.21 | 0.23 | ||||
|
NOTCH4 rs3134931 G>A | G/G |
315 (25) |
183 (28) |
132 (22) |
352 (29) |
200 (35) |
152 (24) | |||
| A/G |
625 (50) |
344 (52) |
281 (47) |
595 (49) |
267 (46) |
328 (52) | ||||
| AA |
314 (25) |
135 (20) |
179 (30) |
266 (22) |
100 (19) |
156 (25) | 0.048 | 2.12E−4 | 2.54E−5 | |
| G |
1255 (50) |
710 (54) |
545 (46) |
1299 (54) |
667 (58) |
632 (50) | ||||
| A |
1253 (50) |
614 (46) |
639 (54) |
1127 (46) |
487 (42) |
640 (50) | 0.014 | 1.46E-4 | 6.29E-5 | |
| PHWE | 0.27 | 0.49 | 0.23 | 0.64 | 0.23 | 0.48 | ||||