Table 3 Risk for gene models in each SNP between the normal and HLPpopulations
SNP | Model | Genotype | Han | Maonan | |||
|---|---|---|---|---|---|---|---|
Reference | Effect | OR (95% CI) | P | OR (95% CI) | P | ||
rs577272 A>G | Co-dominant | A/A | G/A | 0.90 (0.68–1.18) | 0.36 | 1.69 (1.27–2.24) | 0.0011 |
|  |  |  | G/G | 0.77 (0.54–1.10) |  | 1.31 (0.77–2.22) |  |
|  | Dominant | A/A | G/A + G/G | 0.86 (0.66–1.12) | 0.27 | 1.65 (1.25–2.17) | 4E−04 |
|  | Recessive | A/A + G/A | G/G | 0.82 (0.60–1.13) | 0.23 | 0.91 (0.56–1.48) | 0.7 |
|  | Overdominant | A/A + G/G | G/A | 0.99 (0.77–1.26) | 0.92 | 1.60 (1.23–2.08) | 4E−04 |
|  | Log-additive |  |  | 0.88 (0.74–1.05) | 0.16 | 1.36 (1.09–1.71) | 0.0067 |
rs3134931 G>A | Co-dominant | G/G | A/G | 1.32 (0.98–1.78) | < 0.0001 | 1.46 (1.10–1.95) | 0.0016 |
|  |  |  | A/A | 2.33 (1.65–3.29) |  | 1.79 (1.27–2.50) |  |
|  | Dominant | G/G | A/G + A/A | 1.58 (1.19–2.09) | 0.0014 | 1.57 (1.21–2.04) | 7E−04 |
|  | Recessive | G/G + A/G | A/A | 1.94 (1.46–2.57) | < 0.0001 | 1.45 (1.08–1.96) | 0.014 |
|  | Overdominant | G/G + A/A | A/G | 0.86 (0.68–1.10) | 0.24 | 1.17 (0.91–1.50) | 0.24 |
|  | Log-additive |  |  | 1.53 (1.29–1.82) | < 0.0001 | 1.35 (1.14–1.59) | 4E−04 |