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Table 9 Relationship between serum lipid parameters and relative factors in the males and females of the Han and Maonan populations

From: Association between SLC44A4-NOTCH4 SNPs and serum lipid levels in the Chinese Han and Maonan ethnic groups

Lipid Risk factor B Std.error Beta t P
Han/male
 TC Waist circumference 0.016 0.006 0.123 2.640 0.009
  Glucose 0.060 0.028 0.098 2.126 0.034
 TG BMI 0.006 0.003 0.111 2.073 0.037
  Weight − 0.015 0.005 − 0.222 − 3.139 0.002
 HDL-C Weight − 0.018 0.003 − 0.307 − 6.477 2.54E−10
  Alcohol consumption 0.102 0.031 0.158 3.327 0.001
 LDL-C Cigarette smoking − 0.187 0.064 − 0.137 − 2.911 0.004
  BMI 0.031 0.010 0.142 3.052 0.002
  Glucose 0.057 0.024 0.114 2.420 0.016
 ApoA1 Alcohol consumption 0.197 0.015 0.519 12.809 4.48E−7
  Weight − 0.005 0.001 − 0.142 − 3.648 2.97E−4
 ApoB Waist circumference 0.007 0.001 0.262 4.837 1.83E−6
  Glucose 0.020 0.006 0.152 3.472 0.001
 ApoA1/ApoB Waist circumference − 0.011 0.005 − 0.147 − 2.121 0.035
  Alcohol consumption 0.221 0.034 0.300 6.572 1.44E−9
Han/female
 TC Systolic blood pressure 0.011 0.003 0.192 3.394 0.001
  Age 0.009 0.003 0.106 2.437 0.015
 TG Height − 0.014 0.006 − 0.091 − 2.242 0.025
  Waist circumference 0.019 0.006 0.128 3.055 0.002
 HDL-C Waist circumference − 0.011 0.003 − 0.142 − 3.563 3.95E−4
  Pulse pressure 0.002 0.001 0.109 2.803 0.005
 LDL-C Systolic blood pressure 0.005 0.002 0.107 2.566 0.011
  Waist circumference 0.018 0.005 0.149 3.745 1.91E−4
 ApoA1 Cigarette smoking 0.317 0.057 0.215 5.558 4.07E−8
  Weight − 0.005 0.001 − 0.152 − 3.907 1.04E−4
 ApoB Waist circumference 0.007 0.001 0.240 6.191 1.09E−9
  Pulse pressure 0.002 0.001 0.141 3.643 2.92E−4
 ApoA1/ApoB Waist circumference − 0.016 0.003 − 0.202 − 5.172 3.14E−7
  Cigarette smoking 0.580 0.137 0.165 4.225 2.75E−5
Maonan/male
 TC Waist circumference − 0.012 0.001 − 0.276 − 8.270 5.04E−6
  Alcohol consumption 0.131 0.023 0.206 5.594 2.98E−8
 TG Waist circumference − 0.019 0.002 − 0.311 − 9.736 2.53E−7
  Weight 0.010 0.004 0.114 2.541 0.005
  Genotype − 0.06 0.026 − 0.073 − 2.313 0.021
 HDL-C Pulse pressure − 0.002 0.001 − 0.078 − 2.202 0.028
  Alcohol consumption 0.057 0.048 0.113 3.801 5.23E−4
 LDL-C Weight 0.013 0.004 0.170 3.589 3.61E−4
  Alcohol consumption 0.121 0.022 0.265 5.579 4.48E−8
 ApoA1 Waist circumference − 0.007 0.002 − 0.165 − 3.486 0.001
  Glucose − 0.026 0.012 − 0.103 − 2.163 0.031
 ApoB Alcohol consumption − 0.029 0.011 − 0.122 − 2.670 0.008
  Age 0.001 0.001 0.095 2.000 0.046
 ApoA1/ApoB Waist circumference − 0.021 0.003 − 0.293 − 6.435 3.56E−10
  Glucose − 0.043 0.021 − 0.093 − 2.032 0.043
 Maonan/female Age 0.015 0.003 0.193 4.788 2.08E−6
 TC Waist circumference 0.019 0.005 0.153 3.852 1.28E−4
  Glucose − 0.077 0.031 − 0.095 − 2.459 0.014
 TG BMI 0.156 0.049 0.122 3.183 0.002
  Alcohol consumption 0.471 0.165 0.109 2.862 0.004
 HDL-C Weight 0.002 0.001 0.093 2.676 0.008
  Alcohol consumption − 1.066 0.152 − 0.252 − 7.014 5.68E−12
 LDL-C Waist circumference 0.022 0.003 0.242 6.552 1.13E−10
  Alcohol consumption − 0.312 0.044 − 0.260 − 7.023 5.35E−12
 ApoA1 BMI − 0.006 0.002 − 0.100 − 2.708 0.007
  Waist circumference 0.496 0.042 0.399 11.810 2.27E−9
 ApoB Waist circumference 0.005 0.001 0.185 5.353 1.19E−7
  Alcohol consumption − 0.687 0.101 − 0.243 − 6.786 2.54E−11
 ApoA1/ApoB Waist circumference − 0.011 0.002 − 0.182 − 4.942 9.79E−7
  1. The correlation among serum lipid parameters and the genotypes and several environmental factors was determined by multivariable linear regression analyses with stepwise modeling
  2. TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ApoA1 apolipoprotein A1, ApoB apolipoprotein B, ApoA1/ApoB the ratio of apolipoprotein A1 to apolipoprotein B, B unstandardized coefficient, Beta standardized coefficient