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Fig. 4 | Nutrition & Metabolism

Fig. 4

From: S-Equol ameliorates insulin secretion failure through Chrebp/Txnip signaling via modulating PKA/PP2A activities

Fig. 4

S-Equol regulates Chrebp /Txnip signaling in ZDF rats. (a) Western blotting to determine Txnip, Chrebp and Mlx expression in ZDF rats with or without Equol (120 mg/kg.BW.d). (b) Densitometric quantification of the relative folds of the proteins /actin ratio in ZDF rats was shown in bar graph. ZDF, Zucker diabetic fatty rats (fa/fa); ZLR, Zucker lean rats (fa/+). Lane “1 – 4” represents ZLR, Eq + ZLR, ZDF and Eq + ZDF group respectively. Three independent experiments were run and results were presented as means ± SD. # P < 0.05 vs. the Control group, * P < 0.05 vs. ZDF group

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Nutrition & Metabolism

ISSN: 1743-7075

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