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Fig. 7 | Nutrition & Metabolism

Fig. 7

From: Vaspin antagonizes high fat-induced bone loss in rats and promotes osteoblastic differentiation in primary rat osteoblasts through Smad-Runx2 signaling pathway

Fig. 7

Effects of vaspin on osteoblast differentiation gene expression. After primary rat osteoblasts were exposed to various concentrations of vaspin, the mRNA expression of Runx2 (a), Osx (b) and Colla1 (c) was measured by RT-PCR. The mRNA expression of Runx2 (d), Osx (e) and Colla1 (f) in primary rat osteoblasts treated with 50 ng/ml vaspin was detected at different time points. *p < 0.05 compared with control group, #p < 0.05 compared with 10 ng/ml vaspin group, ##p < 0.05 compared with 50 ng/ml vaspin group. The mRNA expression of Runx2 (g) and Osx (h) in femurs of four different groups. Data are expressed as the mean ± SD from three independent experiments. *p < 0.05 compared with ND, #p < 0.05 compared with HFD + vaspin

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Nutrition & Metabolism

ISSN: 1743-7075

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