Skip to main content
Fig. 3 | Nutrition & Metabolism

Fig. 3

From: Ascorbate protects liver from metabolic disorder through inhibition of lipogenesis and suppressor of cytokine signaling 3 (SOCS3)

Fig. 3

Ascorbate disrupts PA-induced hepatic lipid profiles and inhibits lipogenesis. LC/MS lipid profiling of HepG2 cells under PA exposure with two different ascorbate does for 48 h, n = 6. a Expression pattern of TG significantly changed among groups. b Intracellular palmitate (C16:0), palmitoleate (C16:1), stearate (C18:0) and oleic acid (C18:1) content.c-g Lipid desaturation indexes for total lipid species, cardiolipin (CL) and sphingomyelin (SM) respectively (16:1/16:0, 18:1/18:0). h Western blotting for SREBP1. i Relative expression level of lipogenesis related genes in HepG2 cells (n = 3). j Western blotting for SCD1. Statistical significance was assessed with one way ANOVA

Back to article page