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Fig. 4 | Nutrition & Metabolism

Fig. 4

From: Ascorbate protects liver from metabolic disorder through inhibition of lipogenesis and suppressor of cytokine signaling 3 (SOCS3)

Fig. 4

Ascorbate repairs insulin signal transduction by inhibiting SOCS3 expression. a Reltative Socs3 mRNA expression level (n ≥ 5) and b SOCS3 protein content in liver of guinea pig. c Westen blotting for STAT3 and phosphrylational STAT3 (pSTAT3) in guinea pigs’ liver tissue. d Reltative Socs3 mRNA expression level (n ≥ 5) and e SOCS3 protein content in HepG2 cells. f Westen blotting for Stat3 and phosphoryl STAT3 (pSTAT3) in HepG2 cells. Overexpressed SOCS3 in HepG2 cells by lentivirus infection. g Relative mRNA expression level and protein content in cells. h Western blotting for phosphoryl level of insulin signaling pathway related key proteins. Statistical significance was assessed with one way ANOVA

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Nutrition & Metabolism

ISSN: 1743-7075

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