| |
Tertiles of nut consumption
|
|---|
|
T1
|
T2
|
T3
|
Ptrenda
|
|---|
|
Rs7903146
|
|
CC
|
|
Model 1
|
1
|
0.95 (0.63–1.42)
|
0.97 (0.65–1.45)
|
0.97
|
|
Model 2
|
1
|
0.88 (0.58–1.33)
|
0.84 (0.55–1.27)
|
0.71
|
|
Model 3
|
1
|
0.85 (0.56–1.29)
|
0.82 (0.54–1.25)
|
0.63
|
|
CT
|
|
Model 1
|
1
|
0.71 (0.51–0.99)
|
0.64 (0.45–0.90)
|
0.02
|
|
Model 2
|
1
|
0.67 (0.47–0.94)
|
0.61 (0.43–0.87)
|
0.01
|
|
Model 3
|
1
|
0.70 (0.49–0.99)
|
0.63 (0.44–0.90)
|
0.02
|
|
TT
|
|
Model 1
|
1
|
0.80 (0.46–1.39)
|
0.61 (0.34–1.11)
|
0.27
|
|
Model 2
|
1
|
0.79 (0.44–1.41)
|
0.64 (0.35–1.18)
|
0.36
|
|
Model 3
|
1
|
0.78 (0.43–1.42)
|
0.72 (0.39–1.34)
|
0.56
|
|
CT + TT
|
|
Model 1
|
1
|
0.73 (0.55–0.97)
|
0.67 (0.50–0.90)
|
0.01
|
|
Model 2
|
1
|
0.70 (0.52–0.93)
|
0.66 (0.49–0.89)
|
0.01
|
|
Model 3
|
1
|
0.72 (0.54–0.97)
|
0.67 (0.50–0.91)
|
0.02
|
|
Rs12255372
|
|
GG
|
|
Model 1
|
1
|
0.94 (0.64–1.38)
|
1.04 (0.71–1.52)
|
0.86
|
|
Model 2
|
1
|
0.83 (0.55–1.24)
|
0.89 (0.60–1.32)
|
0.65
|
|
Model 3
|
1
|
0.80 (0.53–1.19)
|
0.92 (0.62–1.37)
|
0.54
|
|
GT
|
|
Model 1
|
1
|
0.78 (0.56–1.10)
|
0.77 (0.55–1.08)
|
0.18
|
|
Model 2
|
1
|
0.74 (0.52–1.04)
|
0.68 (0.48–0.96)
|
0.04
|
|
Model 3
|
1
|
0.75 (0.53–1.07)
|
0.67 (0.47–0.95)
|
0.03
|
|
TT
|
|
Model 1
|
1
|
0.53 (0.29–0.98)
|
0.49 (0.26–0.91)
|
0.03
|
|
Model 2
|
1
|
0.58 (0.31–1.09)
|
0.63 (0.32–1.26)
|
0.18
|
|
Model 3
|
1
|
0.66 (0.34–1.26)
|
0.70 (0.35–1.39)
|
0.39
|
|
GT + TT
| |
|
Model 1
|
1
|
0.69 (0.51–0.93)
|
0.69 (0.51–0.93)
|
0.03
|
|
Model 2
|
1
|
0.68 (0.51–0.92)
|
0.66 (0.49–0.90)
|
0.02
|
|
Model 3
|
1
|
0.69 (0.51–0.93)
|
0.66 (0.49–0.69)
|
0.01
|
- Model 1 was crude
- Model 2 was adjusted for age, gender, smoking, physical activity, education levels, occupational status, total energy intake, fiber intake, family history of diabetes, family history of cardiovascular disease
- Model 3 was additionally adjusted for BMI at baseline
- aThe median intake of each tertile category was assigned and then these quartile median variables were included as a continuous variable in cox proportional hazards regression
