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Table 4 Hazard ratios of metabolic syndrome across tertiles of nut consumption according to transcription factor-7-like 2 rs7903146 and rs12255372 genotype among participant with weigh change < 7% during follow-up

From: TCF7L2 polymorphisms, nut consumption, and the risk of metabolic syndrome: a prospective population based study

 

Tertiles of nut consumption

T1

T2

T3

Ptrenda

Rs7903146

CC

    

 Model 1

1

0.80 (0.42–1.50)

0.86 (0.46–1.62)

0.78

 Model 2

1

0.76 (0.39–1.46)

0.69 (0.35–1.36)

0.53

CT

 

 Model 1

1

0.76 (0.48–1.31)

0.85 (0.52–1.39)

0.73

 Model 2

1

0.81 (0.49–1.34)

0.72 (0.42–1.21)

0.32

TT

 

 Model 1

1

0.69 (0.24–1.99)

0.46 (0.13–1.54)

0.44

 Model 2

1

0.51 (0.16–1.61)

0.35 (0.09–1.36)

0.27

CT + TT

 

 Model 1

1

0.73 (0.46–1.14)

0.75 (0.48–1.18)

0.30

 Model 2

1

0.74 (0.46–1.17)

0.63 (0.39–1.02)

0.13

Rs12255372

 

GG

 

 Model 1

1

0.66 (0.36–1.25)

1.07 (0.61–1.88)

0.29

 Model 2

1

0.70 (0.36–1.35)

0.89 (0.47–1.65)

0.40

GT

 

 Model 1

1

0.92 (0.55–1.54)

0.70 (0.41–1.21)

0.19

 Model 2

1

0.85 (0.50–1.43)

0.53 (0.30–0.94)

0.02

TT

 

 Model 1

1

0.58 (0.21–1.65)

0.40 (0.12–1.30)

0.15

 Model 2

1

0.63 (0.21–1.89)

0.95 (0.21–4.20)

0.68

GT + TT

 

 Model 1

1

0.81 (0.51–1.29)

0.66 (0.41–1.07)

0.11

 Model 2

1

0.76 (0.48–1.22)

0.54 (0.32–0.90)

0.02

  1. Model 1 was crude
  2. Model 2 was adjusted for age, gender, smoking, physical activity, education levels, occupational status, total energy intake, fiber intake, family history of diabetes, family history of cardiovascular disease
  3. aThe median intake of each tertile category was assigned and then these quartile median variables were included as a continuous variable in cox proportional hazards regression
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Nutrition & Metabolism

ISSN: 1743-7075

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