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Fig. 1 | Nutrition & Metabolism

Fig. 1

From: A combination of herbal compound (SPTC) along with exercise or metformin more efficiently alleviated diabetic complications through down-regulation of stress oxidative pathway upon activating Nrf2-Keap1 axis in AGE rich diet-induced type 2 diabetic mice

Fig. 1

Designed a representation of flowchart. As shown, acclimation was performed for two weeks. mice with an approximate weight of 14 ± 2 g, were randomly divided into two groups of control (Ctrl) and diabetic mice (DM) that respectively fed with normal diet and (AGE)-rich diet for 16 weeks. After ensuring the emergence of DM, the diabetic group was divided into seven groups randomly (n = 5), as follows: 1. Diabetic mice (DM group), 2. Diabetic mice treated with SPTC (130 mg/kg, DM/SPTC group), 3. Diabetic mice treated with Salvia Officinalis (65 mg/kg, DM/Sal), 4. Diabetic mice treated with metformin (300 mg/kg, DM/Met), 5. Diabetic mice with endurance exercise training (DM/EX), 6.Diabetic mice treated with SPTC + metformin (130 mg/kg + 300 mg/kg respectively, DM/SPTC + Met) 7. Diabetic mice treated with SPTC + exercise training (DM/SPTC + EX)

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Nutrition & Metabolism

ISSN: 1743-7075

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