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Fig. 2 | Nutrition & Metabolism

Fig. 2

From: A combination of herbal compound (SPTC) along with exercise or metformin more efficiently alleviated diabetic complications through down-regulation of stress oxidative pathway upon activating Nrf2-Keap1 axis in AGE rich diet-induced type 2 diabetic mice

Fig. 2

(AGE)-rich diet exacerbates diabetic symptoms in diabetic mice rather than control mice. Control mice (Ctrl) and AGE rich diet-induced diabetic mice, body weight ratios and weight gain percentile (a). Measurement of plasma insulin concentration, HOMA-IR and fasting blood sugar (b). Glucose concentration and area under the curve glucose (c). GLUT4 protein expression in skeletal muscle (d). All values were expressed as mean ± SD (n = 5 per group). #p < 0.05, ##p < 0.01 indicate statistically significant difference in the diabetic mice in comparison to the control mice. Data were analyzed by t-tests

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