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Fig. 4 | Nutrition & Metabolism

Fig. 4

From: A combination of herbal compound (SPTC) along with exercise or metformin more efficiently alleviated diabetic complications through down-regulation of stress oxidative pathway upon activating Nrf2-Keap1 axis in AGE rich diet-induced type 2 diabetic mice

Fig. 4

(AGE)-rich diet impaired by the endogenous redox system in liver. Liver ROS production was measured using DCF fluorescence method, blood ROS level was determined by ELISA Kit (a). Total antioxidant capacity of liver and blood (b). Gpx1, HO1, Nqo1, and Txn expression were measured using qPCR and normalized to 18 s rRNA (c). Nrf2 and Keap1 proteins expression in liver (d). Values were expressed as mean ± SD (n = 5 per group). #p < 0.05 indicates a statistically significant difference in diabetic mice in comparison to the control mice. Data were analyzed by t-tests

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Nutrition & Metabolism

ISSN: 1743-7075

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