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Table 3 The results of two-piecewise linear regression model between total cholesterol and cause-specific mortality

From: A nonlinear association of total cholesterol with all-cause and cause-specific mortality

  All-cause mortality Cardiovascular mortality Cancer mortality
  HR (95% CI) p value HR (95% CI) p value HR (95% CI) p value
Cutoff value, mg/dL 172(4.45 mmol/L) 267(6.90 mmol/L) 205(5.30 mmol/L)
 < Cut-off value 0.60 (0.52, 0.70) < 0.0001 0.99 (0.89, 1.10) 0.8479 0.79 (0.67, 0.93) 0.0058
 ≥ Cut-off value 1.01 (0.96, 1.06) 0.8160 1.38 (1.09, 1.75) 0.0084 1.05 (0.92, 1.21) 0.4612
P for log likelihood ratio test  < 0.001 0.053 0.032
  1. HR, hazard ratio; CI, confidence interval
  2. The two-piecewise linear regression model were adjusted for age, gender, race, education level, married, smoking, body mass index, systolic blood pressure, estimated glomerular filtration rate, high density lipoprotein cholesterol, energy intake, comorbidities (hypertension, and diabetes), and medication use (antihypertensive drugs, hypoglycemic agents, and lipid-lowering drugs)