Fig. 5

BP increased PGC-1α expression via SIRT1. A RT-qPCR of PGC-1α mRNA in mouse liver. PGC-1α expression is expressed relative to GAPDH. B Immunohistochemical staining was used to evaluate SIRT1 expression (Scale bar: 80 μm). C Western blot analysis of hepatic PGC-1α. Date are shown as mean ± SD, n = 8. Lowercase letters (a, b, c, and d) represent significant differences (*P < 0.05, Student’s t-test, n = 8)