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Table 2 Intra-and inter-individual variation of parameters of glucose metabolism during two different MMTTs

From: Impact of mixed meal tolerance test composition on measures of beta-cell function in type 2 diabetes

Variables MMTT-comparison of one meal three times MMTT-comparison of two different meals
iAUC CV
Intra-individual variation (%)
CV
Inter-individual variation (%)
ICC iAUC CV
Intra-individual variation (%)
CV
Inter-individual variation (%)
ICC
C-peptide 672 (276; 1269) 18.2 (2.6; 40.3) 74.2 0.69 759 (377; 1339) 16.9 (0.6; 77.9) 42.7 (41.6; 43.9) 0.51
Insulin 5456 (2363; 9281) 19.7 (2.2; 52.4) 70.5 0.70 7082§ (2473; 17,080) 20.5§ (5.2; 61.8) 69.0§ (64.6; 73.4) 0.59
Glucose 4435 (− 1706; 12,671) 18.9 (− 80.7; 74.9) 207.7 0.89 5276 (810; 15,270) 45.9 (6.9; 97.2) 69.1 (66.6; 71.6) 0.53
  1. Data are means, coefficient of variation (CV), minimum and maximum and intraclass correlation coefficient (ICC). Data are given in ng*ml−1 *3 h−1 for iAUC C-peptide, mU*l−1*3 h−1for iAUC insulin, mg*dl−1*3 h−1 for iAUC glucose
  2. Data are available for §n = 17 out of 20 measurements or n = 27 out of 30 measurements
  3. iAUC, incremental area under the curve; CV, coefficient of variation; ICC, intraclass correlation coefficient; MMTT, mixed meal tolerance test