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Fig. 4 | Nutrition & Metabolism

Fig. 4

From: The long noncoding RNA MALAT1 modulates adipose loss in cancer-associated cachexia by suppressing adipogenesis through PPAR-γ

Fig. 4

MALAT1 is involved in adipogenesis by regulating the transcription of PPAR-γ. a qPCR analyses of the expression of PPAR-γ during the adipogenesis of C3H10 cells. b Immunoblot analyses of the expression of PPAR-γ during C3H10 cells adipogenesis. c qPCR analyses of the expression of PPAR-γ in C3H10 cells without/with knockdown of MALAT1 at differentiation day 6. d Immunoblotting analyses of the expression of PPAR-γ in C3H10 cells without/with knockdown of MALAT1 at differentiation day 6. e The transcriptional activity of the -2 kb region of PPAR-γ in response to MALAT1 or control vector in 293 T cells. The experiments were repeated 3 times. The data represent the means ± SEM. n = 3. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001

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